膀胱に発生したInflammatory Pseudotumorの1例

Abstract

65歳女.無症候性肉眼的血尿に続き, 排尿困難と下腹部膨満感が出現した.腹部超音波検査, 造影CT, MRI, 膀胱鏡検査では, 後壁に, 1cm大の, 淡い造影効果を持つ有茎性非乳頭状腫瘤を認めた.膀胱腫瘍出血に起因する尿閉と診断し, 組織診断深達度目的で経尿道的膀胱腫瘍切除術を行った.腫瘍は核腫大の少ない紡錘形細胞の疎な増生を示し, 小型のリンパ球浸潤がみられたものの, 悪性所見はなかった.又, ビメンチン, α平滑筋抗体が陽性であり, Inflammatory pseudotumorと診断した.術後8ヵ月現在, 再発は認められない.尚, 症例は関節リウマチのため, 約10年にわたるエンドキサンPの内服歴があった

A 65-year-old female was referred to our hospital with a complaint of urinary retention and macrohematuria. Ultrasongraphy, computed tomography, magnetic resonance imaging and cystoscopy revealed a 2 x 2 cm broad-based nonpapillary bladder tumor localized in the anterior wall of the urinary bladder. The clinical diagnosis was an invasive bladder tumor and transurethral resection of bladder tumor carried out for pathological investigation. Finally, we diagnosed it as inflammatory pseudotumor of urinary bladder. No local recurrence was seen 12 months after surgery. Inflammatory pseudotumor of urinary bladder is a relatively rare condition, and this is the 52nd case reported in the Japanese literature.