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タイトル: | Parieto-frontal network in humans studied by cortico-cortical evoked potential. |
著者: | Matsumoto, Riki https://orcid.org/0000-0003-3985-9210 (unconfirmed) Nair, Dileep R Ikeda, Akio https://orcid.org/0000-0002-0790-2598 (unconfirmed) Fumuro, Tomoyuki Lapresto, Eric Mikuni, Nobuhiro Bingaman, William Miyamoto, Susumu Fukuyama, Hidenao Takahashi, Ryosuke https://orcid.org/0000-0002-1407-9640 (unconfirmed) Najm, Imad Shibasaki, Hiroshi Lüders, Hans O |
著者名の別形: | 松本, 理器 |
キーワード: | apraxia cortico-cortical evoked potential epilepsy parieto-frontal network functional connectivity praxis movement |
発行日: | Dec-2011 |
出版者: | Wiley |
誌名: | Human brain mapping |
巻: | 33 |
号: | 12 |
開始ページ: | 2856 |
終了ページ: | 2872 |
抄録: | Parieto-frontal network is essential for sensorimotor integration in various complex behaviors, and its disruption is associated with pathophysiology of apraxia and visuo-spatial disorders. Despite advances in knowledge regarding specialized cortical areas for various sensorimotor transformations, little is known about the underlying cortico-cortical connectivity in humans. We investigated inter-areal connections of the lateral parieto-frontal network in vivo by means of cortico-cortical evoked potentials (CCEPs). Six patients with epilepsy and one with brain tumor were studied. With the use of subdural electrodes implanted for presurgical evaluation, network configuration was investigated by tracking the connections from the parietal stimulus site to the frontal site where the maximum CCEP was recorded. It was characterized by (i) a near-to-near and distant-to-distant, mirror symmetric configuration across the central sulcus, (ii) preserved dorso-ventral organization (the inferior parietal lobule to the ventral premotor area and the superior parietal lobule to the dorsal premotor area), and (iii) projections to more than one frontal cortical sites in 56% of explored connections. These findings were also confirmed by the standardized parieto-frontal CCEP connectivity map constructed in reference to the Jülich cytoarchitectonic atlas in the MNI standard space. The present CCEP study provided an anatomical blueprint underlying the lateral parieto-frontal network and demonstrated a connectivity pattern similar to non-human primates in the newly developed inferior parietal lobule in humans. |
著作権等: | © 2011 Wiley Periodicals, Inc. This is the accepted version of the following article: Human Brain Mapping, 33(12) 2856-2872, which has been published in final form at http://dx.doi.org/10.1002/hbm.2140. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/195915 |
DOI(出版社版): | 10.1002/hbm.21407 |
PubMed ID: | 21928311 |
出現コレクション: | 学術雑誌掲載論文等 |
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