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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| srep24484.pdf | 524.77 kB | Adobe PDF | 見る/開く |
| タイトル: | Oil-free hyaluronic acid matrix for serial femtosecond crystallography. |
| 著者: | Sugahara, Michihiro Song, Changyong Suzuki, Mamoru Masuda, Tetsuya   https://orcid.org/0000-0001-5857-5753 (unconfirmed)Inoue, Shigeyuki Nakane, Takanori Yumoto, Fumiaki Nango, Eriko Tanaka, Rie https://orcid.org/0000-0003-1062-4792 (unconfirmed)Tono, Kensuke Joti, Yasumasa Kameshima, Takashi Hatsui, Takaki Yabashi, Makina Nureki, Osamu Numata, Keiji  https://orcid.org/0000-0003-2199-7420 (unconfirmed)Iwata, So |
| 著者名の別形: | 菅原, 道泰 鈴木, 守 桝田, 哲哉 登野, 健介 岩田, 想 |
| 発行日: | 18-Apr-2016 |
| 出版者: | Nature Publishing Group |
| 誌名: | Scientific reports |
| 巻: | 6 |
| 論文番号: | 24484 |
| 抄録: | The grease matrix was originally introduced as a microcrystal-carrier for serial femtosecond crystallography and has been expanded to applications for various types of proteins, including membrane proteins. However, the grease-based matrix has limited application for oil-sensitive proteins. Here we introduce a grease-free, water-based hyaluronic acid matrix. Applications for proteinase K and lysozyme proteins were able to produce electron density maps at 2.3-Å resolution. |
| 記述: | 結晶を損傷しない新しいタンパク質結晶の輸送媒体を発見－タンパク質の結晶構造解析で新薬創生に一歩近づく. 京都大学プレスリリース. 2016-04-22. |
| 著作権等: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| URI: | http://hdl.handle.net/2433/210352 |
| DOI(出版社版): | 10.1038/srep24484 |
| PubMed ID: | 27087008 |
| 関連リンク: | https://www.kyoto-u.ac.jp/ja/research-news/2016-04-22-0 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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