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タイトル: The dynamics of gyrification in the human cerebral cortex during development
著者: Yoshida, Ririko
Ishizu, Koichi
Yamada, Shigehito  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-8194-6927 (unconfirmed)
Uwabe, Chigako
Okada, Tomohisa  KAKEN_id  orcid https://orcid.org/0000-0003-2312-5677 (unconfirmed)
Togashi, Kaori
Takakuwa, Tetsuya  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-9660-9384 (unconfirmed)
著者名の別形: 高桑, 徹也
キーワード: fetal cerebral hemisphere
gyrification index
magnetic resonance imaging
morphology
three-dimensional reconstruction
発行日: Jan-2017
出版者: Wiley-Blackwell
誌名: Congenital Anomalies
巻: 57
号: 1
開始ページ: 8
終了ページ: 14
抄録: This study quantitatively characterized cortical gyrus folding over human neocortical development by calculating the gyrification index (GI) in 22 human fetal specimens from 16 to 40 weeks with magnetic resonance imaging data. Gl values remained constant at approximately 1.0 until the fetal specimens reached 500 g body weight and 200 mm crown-ramp length (CRL), respectively, and then increased in correlation with the body weight and CRL. The rostrocaudal GI distribution in the cerebral cortex revealed a correspondence of GI peaks with indentations of early-generated primary sulci at 21 weeks of gestation and more frequently increased GI values in the parieto-occipital region than in the fronto-temporal region at 31 and 40 weeks of gestation. These results provide a quantitative reference set for gyrification in normal human cortical development, which may help reveal the mechanism of neurodevelopmental disorders.
著作権等: This is the accepted version of the following article: [Yoshida, R., Ishizu, K., Yamada, S., Uwabe, C., Okada, T., Togashi, K., and Takakuwa, T. (2017) Dynamics of gyrification in the human cerebral cortex during development. Congenital Anomalies, 57: 8–14.], which has been published in final form at http://doi.org/10.1111/cga.12179. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
The full-text file will be made open to the public on 4 JAN 2018 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
This is not the published version. Please cite only the published version.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/217755
DOI(出版社版): 10.1111/cga.12179
PubMed ID: 27500567
出現コレクション:学術雑誌掲載論文等

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