DSpace コレクション: 1996-031996-03http://hdl.handle.net/2433/1151312024-03-29T14:51:25Z2024-03-29T14:51:25Z尿路性器癌を含む重複癌症例の検討深貝, 隆志石原, 理裕船橋, 健二郎内藤, 善文丸山, 邦夫http://hdl.handle.net/2433/1156962021-09-15T09:57:43Z1996-03-01T00:00:00Zタイトル: 尿路性器癌を含む重複癌症例の検討
著者: 深貝, 隆志; 石原, 理裕; 船橋, 健二郎; 内藤, 善文; 丸山, 邦夫
抄録: 当院泌尿器科で発見された尿路性器癌392例の中, 重複癌(三重癌も含む)と診断された42例について臨床的検討を行った. 1)発生頻度は重複癌9.9%, 三重癌0.7%であった.男女比は5:1であった. 2)尿路性器系重複癌の臓器別発生頻度は単発癌のそれとほぼ同じであったが, 前立腺癌にやや多い傾向がみられた. 3)他臓器系の癌の組み合わせでは, 胃癌, 膵癌など消化器系の癌の比率が高い傾向がみられた. 4)発生間隔は同時性(1年未満)16例, 異時性29例で同時性も含め34例の例が5年以内に第二の癌が発生していた; Between October 1980 and December 1994, we treated 392 patients with malignant neoplasms associated with genitourinary organs. We made a statistical study on 42 patients (10.6%) with multiple malignant neoplasms. The average age of 42 patients was 72.2 years and 83% of the patients were male. Malignant neoplasms originating from bladder, prostate or kidney were observed in 19 cases (35%), 19 cases (35%) or 10 cases (11%), respectively. The incidence of prostatic cancer was higher than that in other single primary malignant neoplasms associated with genitourinary organs. The other organs having malignant neoplasms accompanying genitourinary organs were the stomach (39%), lungs (12%), esophagus (9%), and pancreas (9%). Only 16 patients (35%) had synchronous multiple malignant neoplasms. However, 35 cases (75%) including these cases had second primary malignant neoplasms within 5 years of the first. In conclusion, the incidence of multiple malignant neoplasms with genitourinary cancer was as high as 10.6% and the prognosis of these patients was poor. These findings suggest the necessity of careful follow-up on patients with genitourinary cancer.1996-03-01T00:00:00ZEnterococcus faecalisが関与していると思われる腎盂腎炎の臨床的検討石川, 清仁比嘉, 功鈴木, 恵三堀場, 優樹http://hdl.handle.net/2433/1156952021-09-15T09:57:43Z1996-03-01T00:00:00Zタイトル: Enterococcus faecalisが関与していると思われる腎盂腎炎の臨床的検討
著者: 石川, 清仁; 比嘉, 功; 鈴木, 恵三; 堀場, 優樹
抄録: 1)E.faecalisによる難治性腎盂腎炎の臨床的検討を行い, 治療上の問題点を指摘した. 2)難治性腎盂腎炎の起炎菌となりえるE.faecalisの腎への親和性, 病原性は決して低いとはいえない. 3)治療法については臨床症状と菌の消長を考慮し慎重に選択する必要がある; A clinical study was performed in 13 cases of refractory Enterococcus faecalis pyelonephritis that were detected in the Department of Urology, Hiratsuka Municipal Hospital, from April 1975 to March 1995. The characteristic features were that pyelonephritis was commonly seen in females, and clinical symptoms (low-grade intermittent fever, low back pain, general malaise, etc.) were continuously refractory. Bacteriuria or polymicrobial infections were often found, and bacterial count was often as high as 10(2)-10(4)/ml. Nevertheless we considered that E. faecalis caused of refractory pyelonephritis must not have week adherence and pathogenesis to the kidney, owing to the clinical symptoms and the basic subjects. Furthermore this infection was difficult to cure completely with antimicrobials having activity against E. faecalis, and long-term treatment was needed. Therefore, we recommend that treatment for refractory E. faecalis pyelonephritis be carefully selected according to clinical symptoms and the bacterial density of this strain.1996-03-01T00:00:00Z高齢者の浸潤性膀胱腫瘍に対する膀胱亜全摘併用術中照射術の検討小沢, 和紀中込, 一彰米瀬, 淳二児島, 真一辻井, 俊彦佐竹, 一郎田利, 清信砂倉, 瑞良加藤, 真吾楮本, 智子http://hdl.handle.net/2433/1156942021-09-15T09:57:43Z1996-03-01T00:00:00Zタイトル: 高齢者の浸潤性膀胱腫瘍に対する膀胱亜全摘併用術中照射術の検討
著者: 小沢, 和紀; 中込, 一彰; 米瀬, 淳二; 児島, 真一; 辻井, 俊彦; 佐竹, 一郎; 田利, 清信; 砂倉, 瑞良; 加藤, 真吾; 楮本, 智子
抄録: 高齢, 合併症等でhigh riskな浸潤性膀胱腫瘍22例に膀胱亜全摘IORTを施行した.G2は27%, G3は73%, T1+T2は22%, T3+T4は73%であった.5年生存率は41%であり, 5年cause-specific survival rateは75%であった.局所再発は, 術後70月で1例認めたのみで局所の制御は良好であった.副作用は1例に骨盤死腔炎を認めたのみであった.高齢者, 全身状態不良の浸潤性膀胱癌例に膀胱全摘術に準ずる侵襲の少ない手術として, 膀胱亜全摘術+術中照射術は有用である; From 1981 to 1994, intra-operative radiotherapy after subtotal cystectomy was performed on 22 patients with invasive bladder carcinoma on whom radical cystectomy could not be recommended because of old age or condition. All the patients received 25 to 30 Gy of radiotherapy focused on trigonum and internal urethral orifice after subtotal cystectomy with uretero-cutaneostomy. Of 22 patients, 15 patients died. Five patients died of bladder cancer, one died of gastric cancer, one died of rectal cancer and the others died of pneumonia, heart failure, sepsis and senility. The five-year survival rate was 41% and the cause-specific five-year survival rate was 75%. Local recurrence was seen only in one patients, who received second intra-operative radiotherapy and recovered well in complete remission. We believe that intra-operative radiotherapy after subtotal cystectomy is useful for patients with invasive bladder carcinoma on whom radical cystectomy could not be recommended because of old age or condition.1996-03-01T00:00:00Z未治療前立腺癌における治療前PSA値と骨転移との関係影山, 幸雄木原, 和徳鎌田, 成芳長浜, 克志米瀬, 淳二福田, 博志遠坂, 顕永松, 秀樹石坂, 和博辻井, 俊彦北原, 聡史森田, 隆大島, 博幸http://hdl.handle.net/2433/1156932021-09-15T09:57:44Z1996-03-01T00:00:00Zタイトル: 未治療前立腺癌における治療前PSA値と骨転移との関係
著者: 影山, 幸雄; 木原, 和徳; 鎌田, 成芳; 長浜, 克志; 米瀬, 淳二; 福田, 博志; 遠坂, 顕; 永松, 秀樹; 石坂, 和博; 辻井, 俊彦; 北原, 聡史; 森田, 隆; 大島, 博幸
抄録: 血清中PSA濃度が10ng/ml未満の前立腺癌新鮮例では, 組織学的分化度を考慮することにより骨転移のnegative predictive valueを100%とできる可能性が示され, 必ずしも骨シンチグラフィーによる骨転移巣の検索は必要ないと考えられた; We retrospectively reviewed pretreatment levels of serum prostate specific antigen (PSA) in 138 newly diagnosed, untreated patients with prostate adenocarcinoma to evaluate the usefulness of serum PSA levels to predict results of radionuclide bone scans. All of the 24 patients with serum PSA levels above 200 ng/ml showed positive bone scans whereas those with serum PSA levels below 10 ng/ml included only three cases (3/51, 5.1%) positive for bone metastasis. All of the three had poorly differentiated adenocarcinoma of the prostate. In conclusion, bone scans may not be necessary in the cases with serum PSA levels less than 10 ng/ml except for those with poorly differentiated adenocarcinoma.1996-03-01T00:00:00Z