DSpace コレクション: 1993-05
http://hdl.handle.net/2433/116373
1993-052024-03-28T11:22:17ZModification of estimation of the urinary ion-activity products of calcium oxalate and calcium phosphate
http://hdl.handle.net/2433/117850
タイトル: Modification of estimation of the urinary ion-activity products of calcium oxalate and calcium phosphate
著者: Ogawa, Yoshihide
抄録: 蓚酸カルシウム, 燐酸カルシウム, 酸性燐酸カルシウムのイオン活量積の簡易測定法としての諸指数は, 尿中のカルシウム, マグネシウム, 蓚酸, 燐酸, クエン酸, 尿量, pHなどの変数より求められる。それぞれの指数には採尿時間により異なる係数が与えられるが, それぞれの係数は採尿時間と相関する。従って, 係数をその計算式に組み込むことが可能となり, 24時間以内の如何なる採尿時間でせ計算式が利用できるようにした; Tiselius proposed simplified estimates of the ion-activity products of calcium oxalate, calcium phosphate, and brushite as the AP(CaOx) index, the AP(CaP) index, and the AP(Bru) index, respectively, which allowed assessment of the urinary saturation levels of these lithogenic substances. A number of urinary variables (calcium, magnesium, oxalate, phosphate, citrate, urine volume, and pH) are necessary to derive these indices. In addition, these three indices have correction factors corresponding to the urinary collection periods, although these periods were originally quite limited. In this study, the factors were shown to vary as a function of time. Therefore, they were incorporated into these indices after proper calculation so as to be usable for any collection period less than 24 hours. This means that the factors will now prove more useful in evaluating the urinary saturation levels after short-term collections.1993-05-01T00:00:00ZEtiology of asymptomatic microscopic hematuria in adults
http://hdl.handle.net/2433/117849
タイトル: Etiology of asymptomatic microscopic hematuria in adults
著者: Yamamoto, Masanori; Hibi, Hatsuki; Miyake, Koji
抄録: 無症候性顕微鏡的血尿で, 泌尿器科的精査を行った40歳以上の236例のうち, 6.8%に尿路性器癌が発見され, 27.5%に重篤な泌尿器疾患が見いだされた。52.1%の症例においては, 顕微鏡的血尿の原因が不明であった。13.6%の症例において, 重篤ではない泌尿器疾患が見いだされた。40歳以下の72例中16例に異常所見が認められた。これらのうち, 膀胱鏡検査により疾患が発見されたのは, 1例であった。従って若年者に対する膀胱鏡検査はほとんど価値がない。明らかな基礎疾患が見いだされなかった場合は, 三ヵ月ごとに尿検査と尿細胞診を行うことにしている; Asymptomatic microscopic hematuria is a common finding that demands urologic evaluation. Of the 236 patients over the age of 40, 6.8% were found to have a genitourinary cancer, while 27.5% had other significant urologic disease. However, 52.1% of the patients had unknown etiology of microscopic hematuria and 13.6% had insignificant urologic lesions. Of the 72 patients under the age of 40 a positive diagnosis was made in 16 patients (22.2%). Cystoscopic examination was of diagnostic value in only 1 patient. Therefore, cystoscopy is of little diagnostic value in young patients. Once asymptomatic microscopic hematuria is established and no etiological cause is identified, we follow the patient by urinalysis and cytology every three months and reevaluate the patient in whom urological symptoms develop.1993-05-01T00:00:00Z消化管を用いた尿路変向術, 尿路再建術を受けた患者における感染性尿路結石危険因子の検討 : 蓄尿型膀胱と回腸導管の比較
http://hdl.handle.net/2433/117848
タイトル: 消化管を用いた尿路変向術, 尿路再建術を受けた患者における感染性尿路結石危険因子の検討 : 蓄尿型膀胱と回腸導管の比較
著者: 武田, 正之; 片山, 靖士; 高橋, 等; 郷, 秀人; 筒井, 寿基; 西山, 勉; 佐藤, 昭太郎; 中村, 章
抄録: 蓄尿型人工膀胱(リザーバー, R群)12例, 回腸導管術10例(C群)で術施行後2ヵ月で感染性尿路結石の危険因子および予防因子を調べた。両群間に危険因子および複数の危険因子の陽性率に有意差がなかった。しかしR群の4例は複数の危険因子を持ってリザーバー内に結石を生じたが, C群ではなかった。R群では1個の危険因子より複数の危険因子を持つものの結石発生率は有意に高かった。56歳の回腸導管術の症例を提示した; Urinary risk factors and preventive factors for infectious calcium (Ca) urolithiasis formation, such as citrate, oxalate, Ca, phosphate, magnesium, and uric acid were examined more than 2 months after performing a urinary reservoir in 12 patients (R group) and ileal conduit in 10 patients (C group). There was no difference in the positive rate of risk factors between the two groups and also no difference in the positive rate of more than two risk factors between the two groups. Although four patients with more than two risk factors in the R group suffered from reservoir stones all of which included Ca-urolithiasis, none in the C group did. In the R group, the incidence of stone formation in patients with 2 or more risk factors was significantly higher than those in patients with 1 or no risk factor. In conclusion, the urinary reservoir operation should not be carried out in patients with more than two risk factors for urolithiasis formation, and urinary risk factors should be examined before reservoir operation.1993-05-01T00:00:00ZVerapamilが尿中諸物質とくに蓚酸排泄量に及ぼす影響について
http://hdl.handle.net/2433/117847
タイトル: Verapamilが尿中諸物質とくに蓚酸排泄量に及ぼす影響について
著者: 井口, 正典; 池上, 雅久; 際本, 宏; 梅川, 徹; 石川, 泰章; 郡, 健二郎; 栗田, 孝
抄録: 120mg/dayを上部尿路結石症16例に投与した。1)尿中Ca排泄量はverapamil服用前後で差はなかった。過Ca尿症患者(250mg/day以上)で服用前後のCa排泄量を比較しても減少効果はみられなかった。2)尿中蓚酸排泄量は全症例でみると服用前後で差はみられなかったが, 過蓚酸尿症患者(50mg/day以上)でみると著明に減少した。3)尿中クエン酸, マグネシウム排泄量はverapamil服用前後で差はみられなかった。4)蓚酸CaのRisk Indexは全症例でみると服用前後で差はなかったが, 過Ca尿症でしかも過蓚酸尿症のある4例ではverapamil服用によって有意に低下した; The effect of the calcium antagonist verapamil on urinary calcium and oxalate excretion was examined and compared with that of trichlormethiazide to evaluate whether verapamil is useful in the prevention of calcium oxalate renal stones. Twenty-four-hour urine of 16 renal stone formers was measured at the outpatient clinic before and after administration of 120 mg/day verapamil for a mean duration of 2.7 months (range, 2 weeks to 6 months). The 24-hour urine was analyzed for creatinine, calcium, oxalic acid, magnesium and citric acid and the results compared with those in 20 renal stone formers who were administered trichlormethiazide. Verapamil was found to significantly reduce the urinary oxalate excretion of the 5 hyperoxaluric (> or = 50 mg/day) patients but no significant effect on urinary calcium, magnesium or citric acid was observed. Conversely, trichlormethiazide significantly decreased urinary calcium excretion in the hypercalciuric (> or = 250 mg/day) patients. Calcium oxalate risk index of hypercalciuric and hyperoxaluric patients was significantly reduced after the administration of verapamil. These findings suggest that verapamil is effective in reducing urinary oxalate excretion in the hyperoxaluric patients.1993-05-01T00:00:00Z