白血球減少症に対する強力モリアミンSの効果 第2報:X線照射時に於ける白血球減少防止効果について(特に末梢白血球に与える影響)

Abstract

Significant increase in leucocytes in shorter per i o d than control group by administration of the essential amino acid derivative, Moriamin-S, to the experimental animals with severe leucopenia due to administration of anti-cancer substance and significant increase in leucocytes in relatively shorter period by administration of the drug to clinical patients with severe leucopenia due to deep X-Ray therapy and Cobalt therapy have been previously reported from our clinic. This report consists of pr o tective mechanism of Moriamin-S against deep X-Ray therapy on 12 rabbits divided into 5 groups. The results obtained are shown in the table below. 1 Group M.S.* 2cc i.v. injection before radiation 60y x 20 =1, 200y 8, 500-.7, 100 2 Group control 60-yx 2 0 = 1, 200-y 9 , 000 4 , 400 3 Group M.S. lcc i.v. iniection before radiation 60yx 2 0 = 1, 200y 8, 700—> 6 , 400 4 Group M.S. lcc i.v. injection daily for 10 days, total 20cc 60yx 20=1, 200y 8 , 700—, 5, 200 5 Group M.S. 2cc i.v. injection daily for 20 days, total 40cc 60-yx 2 0=1, 200y 8 , 900-.4, 900 * M.S.•••Moriamin-S Those groups which are treated with Moriamin-S proved significant protective mechanism against X-Ray radiation.