尿路腫瘍とホルモン環境 I:下垂体副腎皮質と尿路腫瘍

Abstract

For the clinical investigationso n the pituitary-adre n ocorticasly stem of the patients with urogenital tumor, eosinophilic leukocyte count in the peripheral blood and Thorn test with epinephrinea nd ACTH-Zw ere carried out. 1. Circulatinge osinophils: T he contro l g roup of 25 adults, all older than 45, gave the counts of 57-583p er mm3, m ostly 100-300. In 29 patients with hyperplasia and one with sarcoma of the prostate, eosinophilicc ount was larger than that of 17 patients with carcinoma of the prostate. The former was 273 per mm3 and the latter 121 per mm3 in their average. But there was no remarkable variation noted among other kinds of tumors. Administration of sex hormones raised the count, while castration brought its fall with initial rise. Antineoplastica gents inducedn o remarkablec hanges. 2. SimultaneousT horn test with e pinephrine: The co n trol group of 21 adults showed eosinophils percent fall of 39-70%. In 10 cases with carcinoma of the prostate the percent fall was within 30% except for two cases; on the other hand, 21 of 26 prostatic hypertrophy showed the fall more than 30%. Sex hormones reduced the falling rate, but cortisone gave no remarkable change after the administration of short duration in small dosage. 3. Thorn test with A CTH-Z: T he results were almost same as Thorn t est with epinephrine.