新結石溶解剤Renacidinに関する基礎的実験

Abstract

1. Extracted urinary and biliary calculi were immersed in renacidin solutions of various concentrations and their dissolving processes were observed. Phosphate, carbonate and magnesium phospha t e calculi were markedly dissolved, especially at the concentrations of 10 per cent or more. Oxalate calculi were less dissoluble, and uric acid, cholesterol and bilirubin calculi remained unchanged. 2. A comparative study of solution G, solution M and 10 per cent renacidin solution showed that the latter was the most efficient solvent. 3. Ten per cent renacidin solution gave n o r emz, nIzable changes to the eyes of a rabbit instilled with it once an hour for 6 hours and to the mucous membrane of a newly removed human ureter immersed in it for 24 hours.