治癒切除された腎盂尿管癌症例の予後に関する検討

Abstract

聖隷三方原病院で経験した治癒的切除された腎盂尿管癌30例について検討した.1)pT3とpV1が有意な予後因子であった.2)pT2以上, grade 3成分, pV1が有意な再発危険因子であった.3)治癒的切除された腎盂尿管癌に対して化学療法の有効性は認められなかった

We retrospectively studied 30 patients who underwent curative surgery for renal pelvic and/or ureteral cancer between August 1987 and August 1998. Their clinicopathological features were classified by the criteria of the Japanese Urological Association. The 1-, 3-, and 5-year cause-specific survival rates were, respectively, 100, 95.5, and 85.1%, while the disease-free rates were 100, 78.9, and 78.9% by the Kaplan-Meier method. Prognostic factors were evaluated by the log-rank test. The significant prognostic factors were pT3 and pV1 for cause-specific survival (p = 0.0277, p = 0.0025), while pT2 (or higher), grade 3, and pV1 were significant for disease-free survival (p = 0.0271, p = 0.0327, and p = 0.0002). Nine patients who received adjuvant chemotherapy are alive, but 3 patients have relapsed. Chemotherapy did not have a significant effect on the cause-specific survival or disease-free survival.