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Title: 骨転移を有する腎細胞癌症例の臨床的特徴についての検討 - 肺転移症例との比較検討 -
Other Titles: Clinical study of renal cell carcinoma with bony metastasis: comparative study with lung metastasis
Authors: 大西, 哲郎  KAKEN_name
町田, 豊平  KAKEN_name
増田, 富士男  KAKEN_name
鈴木, 正泰  KAKEN_name
飯塚, 典男  KAKEN_name
中内, 憲二  KAKEN_name
鈴木, 英訓  KAKEN_name
Author's alias: ONISHI, Tetsuro
MACHIDA, Toyohei
SUZUKI, Masayasu
SUZUKI, Hidenori
Keywords: Renal cell carcinoma
Bony metastasis
Issue Date: Jul-1989
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 35
Issue: 7
Start page: 1113
End page: 1118
Abstract: 最近の28年間に慈恵医大および関連病院で経験された,骨に転移を認めた腎細胞癌症例59例(骨のみ転移例は17例)について,臨床的特徴を検討するため,肺転移症例146例(肺のみ転移例は54例)を比較対照として検討した.すなわち,骨転移部位としては,下肢が最も多く32.6%を占め,ついで脊椎,上肢,骨盤,次に肩甲帯,胸郭,頭蓋骨の順となっていた.骨のみ転移例と,肺のみ転移例の生存率を比較すると,3年以後7年まで,骨のみ転移例が転帰良好であった.また,単発転移と多発転移に分けて両者を比較すると,単発骨転移2例(すべて手術的切除例)の予後が良好であった.原発のgrade別に骨のみ転移例と,肺のみ転移例の生存率を比較したが,骨のみ転移例では両grade (low gradeとhigh grade)症例間に有意差はなかった.一方,肺転移ではlow gradeの症例がhigh gradeの症例に比し有意に予後良好であった.従って骨転移については,原発巣の悪性度は肺転移例のそれに比して予後に大きな影響を及ぼさないものと考えられた
For the purpose of clinical analysis of renal cell carcinoma with bony metastasis (59 cases) the cases with lung metastasis (146 cases) were selected for comparison. The analyzed items were the distribution of bony metastatic portions, the results of radiotherapy for bony metastasis, comparative study with lung metastasis on clinical background, comparative study with lung and bony metastasis on the survival rate, comparative study with solitary bony and lung metastasis on the survival rate, comparative study with bony and lung metastasis on the grade of primary lesion. The most frequent metastatic portion was lower extremities, spine, upper extremities and pelvic bone in this order. The survival rate of the cases with bony metastasis was better than that of lung, especially with solitary metastatic cases. The effects of radiotherapy for bony metastasis were not so good for prolonging the survival. The grade of kidney malignancy did not influence the survival of patients with bony metastasis, on the contrary, in patients with lung metastasis, there was a good prognostic factor for survival.
PubMed ID: 2801402
Appears in Collections:Vol.35 No.7

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