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DCフィールド | 値 | 言語 |
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dc.contributor.author | 柿崎, 弘 | ja |
dc.contributor.author | 石井, 延久 | ja |
dc.contributor.author | 鈴木, 騏一 | ja |
dc.contributor.author | 平野, 順治 | ja |
dc.contributor.author | 平野, 和彦 | ja |
dc.contributor.author | 加藤, 弘彰 | ja |
dc.contributor.author | 菅野, 理 | ja |
dc.contributor.author | 村上, 哲 | ja |
dc.contributor.author | 高見沢, 昭彦 | ja |
dc.contributor.author | 水戸部, 勝幸 | ja |
dc.contributor.author | 斎藤, 雅昭 | ja |
dc.contributor.author | 今村, 全 | ja |
dc.contributor.author | 政木, 貴則 | ja |
dc.contributor.author | 松下, 鈆三郎 | ja |
dc.contributor.author | 恩村, 芳樹 | ja |
dc.contributor.alternative | Kakizaki, Hiroshi | en |
dc.contributor.alternative | Ishii, Nobuhisa | en |
dc.contributor.alternative | Suzuki, Kiichi | en |
dc.contributor.alternative | Hirano, Junji | en |
dc.contributor.alternative | Hirano, Kazuhiko | en |
dc.contributor.alternative | Kato, Hiroaki | en |
dc.contributor.alternative | Sugano, Osamu | en |
dc.contributor.alternative | Murakami, Satoru | en |
dc.contributor.alternative | Takamizawa, Akihiko | en |
dc.contributor.alternative | Mitobe, Katsuyuki | en |
dc.contributor.alternative | Saito, Masaaki | en |
dc.contributor.alternative | Imamura, Akira | en |
dc.contributor.alternative | Masaki, Takanori | en |
dc.contributor.alternative | Matsushita, Shozaburo | en |
dc.contributor.alternative | Onmura, Yoshiki | en |
dc.date.accessioned | 2010-06-01T02:14:31Z | - |
dc.date.available | 2010-06-01T02:14:31Z | - |
dc.date.issued | 1990-06 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/116916 | - |
dc.description.abstract | TUR-Pによる治療を施行した前立腺肥大症患者25例に対してCMNX 1 gをone shot静注し, 1時間後の血清, 前立腺組織内濃度について検討した.1) CMNXの血清濃度は69.17±17.47 μg/ml前立腺組織内濃度は5.33±2.33 μg/g, P/S ratioは8.18±4.45%であった.2)血清濃度と前立腺組織内濃度との間には, 相関は認められなかった.3)前立腺組織内濃度と臨床分離株に対するMIC90との比較により, グラム陰性桿菌が起炎菌である細菌性前立腺炎やTUR-P前後の感染症や感染予防に有効であると考えられた | ja |
dc.description.abstract | Carumonam (CRMN), the first monobactam antibiotic in Japan, has excellent activity against gram-negative bacteria and is useful in the treatment of urinary tract infections. However, it may be insufficient in the treatment of complicated urinary tract infections because of the increase in isolation of gram-positive bacteria, and it may be necessary to co-administer antibiotics active against gram-positive organisms to achieve a broader spectrum of coverage in connection with severe infections. The combination of CRMN and fosfomycin (FOM) was evaluated for its effectiveness and safety at the Department of Urology, Yamagata University Hospital and 7 affiliated hospitals. Clinical efficacy was assessed on 64 patients with complicated urinary tract infection according to the Criteria for Clinical Evaluation of Antimicrobial Agents in UTI (3rd. ed.) recommended by the Japan UTI Committee. Clinical efficacy was evaluated as excellent in 16, moderate in 32, poor in 16, with an overall clinical effectiveness rate of 75.0%, which is superior compared with CRMN alone. Of the total of 92 bacterial strains isolated, 66 (71.7%) were eradicated. Subjective adverse reaction was seen in 1 patient (1.4%), as nausea and anorexia. Slight increases in serum GOT and GPT ware recorded in 5 patients (7.1%). These findings disappeared after the termination of administration without treatment. The combination of CRMN and FOM might therefore be useful in the treatment of complicated urinary tract infections. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Aztreonam/administration & dosage/analogs & derivatives/therapeutic use | en |
dc.subject | Chronic Disease | en |
dc.subject | Drug Therapy, Combination/administration & dosage/therapeutic use | en |
dc.subject | Female | en |
dc.subject | Fosfomycin/administration & dosage/therapeutic use | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Urinary Tract Infections/drug therapy/microbiology | en |
dc.subject.ndc | 494.9 | - |
dc.title | 複雑性尿路感染症に対するカルモナム(CRMN),ホスホマイシン(FOM) 2剤併用の臨床的検討 | ja |
dc.title.alternative | Clinical evaluation of the combination of carumonam and fosfomycin in the treatment of complicated urinary tract infection | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 36 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 731 | - |
dc.identifier.epage | 735 | - |
dc.textversion | publisher | - |
dc.sortkey | 18 | - |
dc.address | 山形大学医学部泌尿器科学教室 | ja |
dc.address | 山形県立河北病院泌尿器 | ja |
dc.address | 山形県立新庄病院泌尿器科 | ja |
dc.address | 山形県立中央病院泌尿器科 | ja |
dc.address | 山形市立病院済生館泌尿器科 | ja |
dc.address | 市立酒田病院泌尿器科 | ja |
dc.address | 鶴岡市立荘内病院 | ja |
dc.address | 長井市立総合病院泌尿器 | ja |
dc.address.alternative | The Department of Urology, Yamagata University School of Medicine | en |
dc.address.alternative | The Department of Urology, Yamagata Prefectural Kahoku Hospital | en |
dc.address.alternative | The Department of Urology, Yamagata Prefectural Shinjo Hospital | en |
dc.address.alternative | The Department of Urology, Yamagata Central Prefectural Hospital | en |
dc.address.alternative | The Department of Urology, Yamagata City Hospital Saiseikan | en |
dc.address.alternative | The Department of Urology, Sakata City Hospital | en |
dc.address.alternative | The Department of Urology, Tsuruoka City Shonai Hospital | en |
dc.address.alternative | The Department of Urology, Nagai City Hospital | en |
dc.identifier.pmid | 2239570 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.36 No.6 |
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