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タイトル: | 慢性複雑性尿路感染症に対するOfloxacin (OFLX)の臨床的検討 |
その他のタイトル: | Clinical evaluation of ofloxacin in the treatment of chronic complicated urinary tract infection |
著者: | 打林, 忠雄 西野, 昭夫 久住, 治男 沢木, 勝 長野, 賢一 元井, 勇 折戸, 松男 庄田, 良中 小橋, 一功 菅田, 敏明 |
著者名の別形: | Uchibayashi, Tadao Nishino, Akio Hisazumi, Haruo Sawaki, Masaru Koizumi, Hisashi Nagano, Kenichi Orito, Matsuo Shyoda, Ryochu Kobashi, Kazunori Sugata, Toshiaki |
キーワード: | Administration, Oral Adolescent Adult Aged Aged, 80 and over Chronic Disease Female Humans Male Middle Aged Ofloxacin/administration & dosage/adverse effects/therapeutic use Urinary Tract Infections/drug therapy/microbiology |
発行日: | Jun-1990 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 36 |
号: | 6 |
開始ページ: | 725 |
終了ページ: | 730 |
抄録: | Ofloxacin was administered orally at a daily dosage of 300 mg and 600 mg in three divided doses for 14 days to 24 and 60 patients with chronic complicated urinary infections, respectively, in order to evaluate the therapeutic efficacy. The clinical efficacy was evaluated according to the criterion proposed by the UTI Committee in Japan and its efficacy was evaluated in 84 cases. In the group of 24 patients receiving a daily dosage of 300 mg, the clinical effectiveness after a 5-day treatment was excellent in 13 cases and moderate in 7 cases. The overall clinical efficacy was 83.8%. In the group of 60 patients receiving a daily dosage of 600 mg, the rate of overall clinical efficacy after a 5-day treatment was 83.3%, being excellent in 23 cases and moderate in 27 cases. The eradication rate was 85.3% and 92.5% by 300 mg and 600 mg dosages of ofloxacin, respectively. As adverse reactions, anorexia and nausea occurred in 2 cases. Laboratory anomalies consisted of 1 case of slight and transient elevation of transaminase, and 1 case of elevated serum creatinine. |
URI: | http://hdl.handle.net/2433/116917 |
PubMed ID: | 2239569 |
出現コレクション: | Vol.36 No.6 |
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