シンナー濫用による神経因性膀胱の1例

Abstract

A 23-year-old man consulted the urological department of our hospital with a complaint of urinary retention. He had consulted the department of ophthalmology for decreased vision and visual defect in both of his eyes of 1 year duration. Urodynamic study revealed detrussor hyporeflexia. Neurologically cerebellar signs were seen. Auditory brain stem response and visual evoked potential revealed damage of the pons. Magnetic resonance imaging revealed atrophy of the cerebrum and cerebellum, dilatation of the fourth ventricle and loss of gray/white differentiation of the brain stem on T2-weighted sequence. Urinary level of hippuric acid was markedly high and the neurogenic bladder was considered to have been induced by the demyelinization at the pons which was caused by chronic toluene abuse.