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Title: Cisplatin,Vincristine,Methotrexate,Peplomycin,Etoposideによる"COMPE"多剤併用化学療法が著効を奏した精巣絨毛癌の1例
Other Titles: A case of testicular choriocarcinoma achieving pathological complete response by "COMPE" chemotherapy, consisting of cisplatin, vincristine, methotrexate, peplomycin, and etoposide
Authors: 大野, 芳正  KAKEN_name
山内, 民男  KAKEN_name
上田, 朋宏  KAKEN_name
相澤, 卓  KAKEN_name
川上, 理  KAKEN_name
立花, 裕一  KAKEN_name
河合, 恒雄  KAKEN_name
中川, 健  KAKEN_name
土屋, 繁  KAKEN_name
Author's alias: Ohno, Yoshio
Yamauchi, Tamio
Ueda, Tomohiro
Aizawa, Taku
Kawakami, Satoru
Tachibana, Yuichi
Kawai, Tsuneo
Nakagawa, Ken
Tsuchiya, Shigeru
Keywords: Testicular cancer
Choriocarcinoma
Chemotherapy
Issue Date: Feb-1993
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 39
Issue: 2
Start page: 183
End page: 187
Abstract: We report a case of pure choriocarcinoma of the left testis in a 27-year-old male. He consulted a physician with left back pain in August, 1990. Intravenous pyelography (IVP) revealed left hydronephrosis. Abnormal computerized tomography (CT) revealed para-aortic lymph node swelling. The chest X-ray revealed bilateral multiple coin lesions. The genital examination revealed a left testicular nodule 8 mm in diameter. Left high inguinal orchiectomy was performed. Histopathological diagnosis was pure choriocarcinoma. After 4 courses of the PVB (cisplatin, vinblastine, bleomycin) therapy, tumor regression rate of the pulmonary metastases was 41.9%. He was transferred to our hospital on December 3, 1990 and was admitted 3 days later. "COMPE" chemotherapy, consisting of cisplatin, vincristine, methotrexate, peplomycin, and etoposide, was administered. After seven courses of "COMPE" chemotherapy, he achieved a partial response (the regression rate of the pulmonary metastases and the retroperitoneal lymph node metastasis were 78.8% and 69.1%, respectively) and the residual masses in the lungs and the retroperitoneum were removed. Necrosis and xanthogranulomatous fibrosis were found in the resected material. The patient showed no evidence of disease one year after thoracotomy.
URI: http://hdl.handle.net/2433/117772
PubMed ID: 7682032
Appears in Collections:Vol.39 No.2

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