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Title: Prostatic cancer presenting monoclonal gammopathy: report of two cases
Other Titles: 単クローン性形質細胞増多症を示した前立腺癌の2例
Authors: Tsutsumi, Masakazu
Hara, Toru
Fukasawa, Ritsu
Koiso, Kenkichi
Author's alias: 堤, 雅一
原, 徹
深沢, 立
小磯, 謙吉
Keywords: Prostatic cancer
Monoclonal gammopathy
Bence Jones protein
Issue Date: Jun-1993
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 39
Issue: 6
Start page: 569
End page: 572
Abstract: われわれは単クローン性形質細胞増多症(MGUS)を示した前立腺癌を2例経験した.2例ともIgG一λタイプのMGUSであり,尿中にペンスジョーンズ蛋白が認められた.2例を通して特微的なことは多発性の骨転移が認められたことであった.1例は著じるしい免疫不全状態を示し,治療によってMGUSの改善が認められた.高齢の男性でMGUSを示した症例は,前立腺癌の可能性を一度考える必要があると思われた.
Two cases of prostatic cancer accompanied by monoclonal gammopathy of undetermined significance (MGUS) are reported. Both cases presented IgG-lambda type hyperimmunoglobulinemia and Bence Jones protein (BJP) in the urine. A characteristic of both cases was significant multiple bone metastasis, and one case also demonstrated a severe immunological disorder. During the treatment, one patient recovered from MGUS. We recommend that elderly male patients manifesting MGUS be examined for prostatic cancer.
PubMed ID: 8337985
Appears in Collections:Vol.39 No.6

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