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タイトル: 真菌が関与したと思われる単純性尿路感染症の検討と5-FCの有用性の評価
その他のタイトル: The study of urinary tract infection with a possible cause of fungi and evaluation of the efficacy of 5-FC
著者: 鈴木, 恵三  KAKEN_name
玉井, 秀亀  KAKEN_name
著者名の別形: Suzuki, Keizo
Tamai, Hideki
キーワード: Adolescent
Adult
Anti-Bacterial Agents
Anti-Infective Agents/therapeutic use
Candida albicans/drug effects
Candidiasis/drug therapy/microbiology
Cytosine/analogs & derivatives
Drug Evaluation
Drug Resistance, Microbial
Drug Therapy, Combination
Female
Flucytosine/metabolism/pharmacology/therapeutic use
Humans
Middle Aged
Ofloxacin
Oxazines/therapeutic use
Urinary Tract Infections/drug therapy/microbiology
発行日: Oct-1985
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 31
号: 10
開始ページ: 1885
終了ページ: 1894
抄録: Prior to clinical investigations, in vitro activities of 5-fluorocytosine (5-FC), ofloxacin (OFLX), and the combination on a strain of E. coli and of C. albicans were tested. The two drugs showed highly active on each target strain without any interaction. In clinical studies, 5 female adult patients with persistent uncomplicated UTI (3 of cystitis, 2 of pyelonephritis) caused by polymicrobial organisms (including bacteria and fungi) were treated in combination of 5-FC and oral chemotherapeutic agent. The results were both bacteriologically and symptomatically successful in all of 5 cases. Those had been poor by other antibiotic drugs in single use or 5-FC alone. Consequently, 5-FC and oral antibacterial drug combination was useful in therapy on even uncomplicated UTI due to polymicrobial organisms including fungi.
URI: http://hdl.handle.net/2433/118617
PubMed ID: 3911766
出現コレクション:Vol.31 No.10

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