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タイトル: | 真菌が関与したと思われる単純性尿路感染症の検討と5-FCの有用性の評価 |
その他のタイトル: | The study of urinary tract infection with a possible cause of fungi and evaluation of the efficacy of 5-FC |
著者: | 鈴木, 恵三 玉井, 秀亀 |
著者名の別形: | Suzuki, Keizo Tamai, Hideki |
キーワード: | Adolescent Adult Anti-Bacterial Agents Anti-Infective Agents/therapeutic use Candida albicans/drug effects Candidiasis/drug therapy/microbiology Cytosine/analogs & derivatives Drug Evaluation Drug Resistance, Microbial Drug Therapy, Combination Female Flucytosine/metabolism/pharmacology/therapeutic use Humans Middle Aged Ofloxacin Oxazines/therapeutic use Urinary Tract Infections/drug therapy/microbiology |
発行日: | Oct-1985 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 31 |
号: | 10 |
開始ページ: | 1885 |
終了ページ: | 1894 |
抄録: | Prior to clinical investigations, in vitro activities of 5-fluorocytosine (5-FC), ofloxacin (OFLX), and the combination on a strain of E. coli and of C. albicans were tested. The two drugs showed highly active on each target strain without any interaction. In clinical studies, 5 female adult patients with persistent uncomplicated UTI (3 of cystitis, 2 of pyelonephritis) caused by polymicrobial organisms (including bacteria and fungi) were treated in combination of 5-FC and oral chemotherapeutic agent. The results were both bacteriologically and symptomatically successful in all of 5 cases. Those had been poor by other antibiotic drugs in single use or 5-FC alone. Consequently, 5-FC and oral antibacterial drug combination was useful in therapy on even uncomplicated UTI due to polymicrobial organisms including fungi. |
URI: | http://hdl.handle.net/2433/118617 |
PubMed ID: | 3911766 |
出現コレクション: | Vol.31 No.10 |
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