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タイトル: | 原発性副甲状腺機能亢進症の1例 : 経口Ca負荷試験による高Ca尿症の評価 |
その他のタイトル: | A case report: primary hyperparathyroidism--comparison before and after parathyroidectomy by oral calcium tolerance test |
著者: | 坂本, 亘 川島, 秀紀 西島, 高明 千住, 将明 岸本, 武利 前川, 正信 |
著者名の別形: | SAKAMOTO, Wataru KAWASHIMA, Hideki NISHIJIMA, Takaaki SENJU, Masaaki KISHIMOTO, Taketoshi MAEKAWA, Masanobu |
キーワード: | Primary hyperparathyroidism Ca tolerance test Hypercalciuria Parathyroid suppressibility |
発行日: | Dec-1987 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 33 |
号: | 12 |
開始ページ: | 2084 |
終了ページ: | 2089 |
抄録: | To evaluate the cause of hypercalciuria, we carried out the oral calcium tolerance test before and after parathyroidectomy in a patient with primary hyperparathyroidism who had recurrent and multiple nephrolithiasis. Preoperative laboratory examination showed hypercalcemia, hypophosphetamia, hypercalciuria, decrease in % tubular reabsorption of phosphorus and strikingly elevated urinary cyclic AMP excretion. The oral calcium tolerance test indicated a significantly greater increase in serum calcium (delta serum calcium: 1.4 mg/dl vs 0.8 mg/dl) and a significantly greater suppression of urinary cyclic AMP excretion (delta U-cyclic AMP:-3.56 moles/gCre vs-1.17 moles/gCre) before parathyroidectomy than after. These results showed that hypercalciuria in this case was induced not only by the significant increase in the filtrated load of calcium but by the reduction in the resorption of calcium in the distal tubule caused by the significantly suppressed parathyroid hormone effect. |
URI: | http://hdl.handle.net/2433/119380 |
PubMed ID: | 2834926 |
出現コレクション: | Vol.33 No.12 |
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