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タイトル: | 尿路感染症の薬剤耐性とNalidixic Acidの治験について |
その他のタイトル: | Nalidixic acid (Wintomylon) and bacterial resistance to antibiotics in urinary tract infections |
著者: | 牧野, 昌彦 ![]() |
著者名の別形: | Makino, Masahiko |
キーワード: | Bacteria/drug effects Chloramphenicol/pharmacology Drug Resistance, Microbial Escherichia coli/drug effects Humans Kanamycin/pharmacology Nalidixic Acid/therapeutic use Oleandomycin/pharmacology Streptomycin/pharmacology Tetracycline/pharmacology Urinary Tract Infections/drug therapy/microbiology |
発行日: | Jun-1968 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 14 |
号: | 6 |
開始ページ: | 351 |
終了ページ: | 356 |
抄録: | A total of 282 organisms isolated during the year of 1966 from ambulatory patients with urinary tract infection at the Anjoh Kosei Hospital, Anjoh, were examined for percentage frequency of isolation as well as percentage resistance to a series of eight antibiotics by the bacterial species, for degree of their pathogenicity to urinary tract infection, and for the presence of multiple resistance to antibiotics, For inhibition of the growth of E. coli in vitro, the most effective agents were Nalidixic acid and PanfuranS followed, in order, by kanamycin, cephaloridine, colimycin, streptomycin, chloramphenicol and tetracycline, A clinical trial with the narrow-spectrum antibacterial agent Wintomylon (nalidixic acid) which thus showed the lowest MIC values against E. coli was conducted in a series of 124 patients with urinary tract infection, and the results obtained confirmed its potential usefulness in this disease state. |
URI: | http://hdl.handle.net/2433/119869 |
PubMed ID: | 4882490 |
出現コレクション: | Vol.14 No.6 |
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