両側性Spermatocytic Seminomaの1例

Abstract

A 70-year-old male was hospitalized because of enlargement of both scrotal contents. Surgical exploration revealed the tumor of the both testes, and bilateral orchiectomy was performed. The organs were found to be replaced entirely by neoplastic growth of grey-white in color. Microscopic studies showed a rather unusual pattern of seminoma which was compatible with spermatocytic seminoma. The tumor consited of diffuse sheet of neoplastic cells variable in shape and size with large round nuclei. The mitotic activity was quite prominent. The fibrous stroma was only scant and devoid of lymphocytic infiltration. Histochemistry failed to demonstrate any reticulin formation, thus ruling out possibility of reticulum-cell sarcoma. The patient is doing well after one year of postoperative follow-up period without any sign of metastasis. Some literatures were reviewed on incidence, age, pathology, treatment, prognosis and histogenesis of this special type of testicular tumor.