64.9%iodamideを使用したdrip infusion pyelographyの検討

Abstract

Drip infusion pyelography was performed with 100 ml of a 64.9 per cent methylglucamine iodamide solution diluted with the same volume of a 5 per cent glucose solution in 96 cases in which visualization by routine intravenous pyelography was unsatisfactory or entirely absent, and its diagnostic contribution and safety were studied. By this technique better urograms were obtained than those by routine intravenous pyelography. Fine urograms could be obtained even in cases with ureteral obstruction, in post-operative cases of uretero-vesical anastomosis or in cases of children. This was quite helpful because retrograde pyelography was impossible in any of these cases. Diagnostic urograms were obtained in about 50 per cent of the cases with unilateral renal disease in which visualization was unsatisfactory or absent by routine intravenous pyelography, and in 43 per cent of the cases with renal impairment with BUN less than 40 mg/dl. In these cases, therefore, retrograde pyelography was omitted. Regarding safety, there were no severe side effects and the influence on pulse, blood pressure, BUN, serum electrolytes and renal function was slight. Particularly it was relatively safe in the cases with renal insufficiency. It can be concluded, accordingly, that drip infusion pyelography with 100ml of a 64.9 per cent iodamide solution is safe and it can be regarded as an excellent technique of urography.