クッシング症候群9例の臨床的観察 われわれの教室における副腎疾患の臨床 - その2 -

Abstract

1) Nine cases of Cushing's syndrome have been treated in our department. As for histopathological findings of the adrenal, one was bilateral cortical adenoma and 7 cases were adrenal hyperplasia. 2) As for the treatment, bilateral total adrenalectomy was done in 5 cases of adrenal hyperplasia. In one case this procedure was done after pituitary irradiation by cobalt. Subtotal adrenalectomy was done in 2 cases, and one of them died and another one required further treatment with pituitary irradiation and total adrenalectomy. The remaining one patient was treated with pituitary irradiation alone. One patient with bilateral adrenal cortical adenoma underwent bilateral total adrenalectomy. 3) Of the 5 patients who underwent bilateral total adrenalectomy for hyperplasia, 4 had remission or improvement. Of the 2 patients treated by subtotal adrenalectomy, one required pituitary irradiation and total adrenalectomy and one died. The patient treated by pituitary irradiation alone improved. The patient with bilateral adrenal cortical adenoma improved after bilateral total adrenalectomy. Postoperative course was uneventful and shows no sign of recurrence and Nelson's syndrome.