前立腺抽出物(Robaveron)の排尿機能におよぼす影響についての実験的研究2 家兎における神経因性膀胱(脊損膀胱,脳膀胱)の作成について

Abstract

Experimental study of the neurogenic bladder was carried out on rabbits. Spinal rabbits (upper motor neuron type and lower motor neuron type) were induced by transsection of the spinal cord. Brain bladders were also induced by injury to the superior colliculus or inferior colliculus. It is not difficult to apply these operations to rabbits and survive them for long time; furthermore they are available as the model of clinical picture. Pathological findings and pathological involvements of nerve fibers in detrusor muscle were reported here. On the experiment of brain bladder, the following results were obtained. The injury of the superior colliculus caused reflex bladder and the injury of the rostal part of it caused uninhibited neurogenic bladder, moreover the superior colliculus played an important role in the inhibition of bladder contraction.