Hemofiltrationの研究, Naの動態について

Abstract

Comparative study on sodium kinetics was performed between hemofiltration(HF) and hemodialysis (HD). Five of 12 patients with chronic renal failure were treated by HF and others were by HD. Procedures were started later than 12 hours after oral administration of [22]Na. The concentrations of total Na and [22]Na in serum and total removal amount of [22]Na in HF and HD were measured. Although total removal amount of [22]Na was significantly larger in HF than in HD and body weight loss was comparable between the patients on HF and on HD, the disappearance curve of serum 22Na concentration in HF was delayed more significantly than that in HD. But total serum Na concentrations did not significantly change during both HF and HD. The results indicate that sodium is equilibrated more efficiently between the intravascular space and other spaces by convective mass transfer in hemofiltration.