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タイトル: RIA法による前立腺性酸フォスファターゼの診断的価値
その他のタイトル: THE EVALUATION OF RADIOIMMUNOASSAY FOR PROSTATIC ACID PHOSPHATASE
著者: 藤井, 光正  KAKEN_name
瀧原, 博史  KAKEN_name
安井, 平造  KAKEN_name
越戸, 克和  KAKEN_name
酒徳, 治三郎  KAKEN_name
小林, 勝昌  KAKEN_name
著者名の別形: Fujii, Mitsumasa
Takihara, Hiroshi
Yasui, Heizo
Koshido, Yoshikazu
Sakatoku, Jisaburo
Kobayashi, Katsuaki
発行日: Oct-1980
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 26
号: 10
開始ページ: 1263
終了ページ: 1270
抄録: The measurement of human prostatic acid phosphatase (PAP) was studied using PAP RIA KIT which was first established in Japan by Eiken Immunochemical Laboratory. The immunological activity of PAP was stable for 24 hours at room temperature and had no cross-reactivity with erythrocytes. In the clinical phase, PAP was measured in the serum obtained from 37 patients with benign prostatic hypertrophy, 47 patients with treated and untreated prostatic cancer, 43 patients with other urological diseases and 31 volunteers of healthy adult men. From this result, it was concluded that the normal range of PAP was less than 3.19ng/ml. In the group of untreated prostatic cancer, the positivity of PAP by radioimmunoassay was 78% in stage III and 100% in stage IV. In both stages, it was higher than that of enzymatic assay. False positive by radioimmunoassay was 5 to 10%, and false negative 14%. As conclusion the method of radioimmunoassay for measurement of PAP is much more reliable than enzymatic assay.
URI: http://hdl.handle.net/2433/122749
出現コレクション:Vol.26 No.10

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