尿路悪性腫瘍を含む重複癌の臨床的検討

Abstract

Reports on multiple primary malignant tumors have been increasing in recent years as the lifespan has prolonged remarkably due to the astonishing advancement in modern medicine. Six patients with multiple malignant tumors associated with genitourinary organs were seen at our urological department during the five years starting from October 1, 1976. We describe the results of the clinical studies made on these 6 patients and review the pertinent literature. Results of clinical studies described are summarized as follows: 1) Patients' ages ranged from 72 to 77 years. Male to female ratio was 5 to 1. 2) Bladder tumor was found in 4 patients, and prostate cancer and penile cancer in 1 patient each. 3) The primary organs of malignancies other than genitourinary organs were sigmoid colon in 3 patients and stomach, pancreas and lung in 1 patient each. 4) The two primary tumors were diagnosed simultaneously in 3 patients and within 18 months in 3 patients. 5) As expected after diagnoses of secondary primary malignancy, the prognoses of the patients were not good. All patients except 2 died within 12 months. One patient has been living for more than 24 months despite the presence of unresectable in situ sigmoid colon cancer. Another has been in hospital for more than 2 months after surgery.