原発巣摘除後,骨および肺転移巣の消退をきたした腎癌の1例

Abstract

A 57-year-old man was admitted to our hospital on August 7, 1978 with the chief complaint of left leg pain and claudication. Physical examination revealed a huge, hard, smooth, movable mass in left flank. Chest film showed multiple nodular tumors in both lungs. Osteolytic lesion in left fibula was noted by bone survey. IVP and angiography confirmed left renal tumor. Left nephrectomy was performed on September 18, 1978. The specimen weighed 1130 grams and measured 19.0×9.5×8.0 cm. Histopathological diagnosis was adenocarcinoma of the left kidney. Postoperatively, FT-207 was given 750 mg a day as adjuvant chemotherapy. One year after nephrectomy, X-rays revealed regression of the pulmonary and fibular metastases. Whether nephrectomy should be indicated in stage D renal carcinoma has been controversial. Although the percentage to induce spontaneous regression of metastases following nephrectomy is very low, the present case allures us to perform adjunctive nephrectomy in the good risk stage D cases.