前立腺肥大症に対するAllylestrenol(Gestanon)の臨床的効果 - 経直腸的超音波断層法による前立腺の形態および重量の変化について -

Abstract

Nine patients with benign prostatic hypertrophy were treated with a progestational agent, Allylestrenol (Gestanon), 30 mg daily for three months to one year. As the control, 10 patients with prostatic hypertrophy were treated with Eviprostat, a non-hormonal remedy consisting of plant extracts, 6 tablets daily for the same duration. Subjective symptoms of 7 patients who had received Eviprostat and those of 8 patients who had received Gestanon were improved significantly. There was no reduction in size or weight of the prostate after three months to one year of treatment with Eviprostat, as measured by transrectal ultrasonotomography, but remarkable reduction in size and weight of the prostate was observed after three months in 6 of the patients treated with Gestanon. The prostate continued to be reduced gradually for one year. There were no side effects following administration of Gestanon.