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Title: Lipid outward translocation by ABC proteins
Authors: Nagao, Kohjiro
Kimura, Yasuhisa  kyouindb  KAKEN_id
Mastuo, Michinori
Ueda, Kazumitsu  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0003-2980-6078 (unconfirmed)
Author's alias: 植田, 和光
Keywords: ABC protein
Transporter
Lipid
Flip-flop
Cholesterol
Membrane
Issue Date: 2-Jul-2010
Publisher: Elsevier B.V.
Journal title: FEBS letters
Volume: 584
Issue: 13
Start page: 2717
End page: 2723
Abstract: In humans, about 50 ABC proteins play physiologically important roles. Many ABC proteins are involved in lipid outward translocation and lipid homeostasis in the body, and defects in their functions cause various diseases. However, the precise mechanisms of substrate transport remain unclear. In bacteria, several ABC proteins are involved in the transport of lipoproteins and lipopolysaccharides from the inner to outer membrane, and their functioning is a prerequisite for survival. Their functions can be divided into "flip-flop" and "projection". In this review, human ABC proteins are compared to bacterial proteins to elucidate their mechanisms.
Description: Lipid outward translocation by ABC proteins. Edited by Wilhelm Just (Review)
Rights: © 2010 Federation of European Biochemical Societies Published by Elsevier B.V.
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/126737
DOI(Published Version): 10.1016/j.febslet.2010.04.036
PubMed ID: 20412807
Appears in Collections:Journal Articles

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