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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| journal.pone.0016081.pdf | 686.24 kB | Adobe PDF | 見る/開く |
| タイトル: | The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. |
| 著者: | Murakami, Yoshiki Toyoda, Hidenori Tanaka, Masami Kuroda, Masahiko Harada, Yoshinori Matsuda, Fumihiko   Tajima, Atsushi Kosaka, Nobuyoshi Ochiya, Takahiro Shimotohno, Kunitada |
| 著者名の別形: | 村上, 善基 |
| 発行日: | Jan-2011 |
| 出版者: | Public Library of Science(PLoS) |
| 誌名: | PloS one |
| 巻: | 6 |
| 号: | 1 |
| 論文番号: | e16081 |
| 抄録: | Chronic hepatitis C (CH) can develop into liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully understood. microRNAs (miRNAs) are now essential to the molecular mechanisms of several biological processes. In order to clarify how the aberrant expression of miRNAs participates in development of the liver fibrosis, we analyzed the liver fibrosis in mouse liver fibrosis model and human clinical samples. |
| 著作権等: | © 2011 Murakami et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| URI: | http://hdl.handle.net/2433/138231 |
| DOI(出版社版): | 10.1371/journal.pone.0016081 |
| PubMed ID: | 21283674 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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