ダウンロード数: 443
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
j.ejrad.2009.11.019.pdf | 2.66 MB | Adobe PDF | 見る/開く |
タイトル: | The potential clinical value of FDG-PET for recurrent renal cell carcinoma. |
著者: | Nakatani, Koya Nakamoto, Yuji https://orcid.org/0000-0001-5783-8048 (unconfirmed) Saga, Tsuneo https://orcid.org/0000-0001-7801-9316 (unconfirmed) Higashi, Tatsuya Togashi, Kaori |
著者名の別形: | 中谷, 航也 |
キーワード: | 18F-FDG-PET Renal cell carcinoma Recurrence Prognostic value |
発行日: | Jul-2011 |
出版者: | Elsevier Ireland Ltd. |
誌名: | European journal of radiology |
巻: | 79 |
号: | 1 |
開始ページ: | 29 |
終了ページ: | 35 |
抄録: | Purpose:The clinical value of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) for follow-up or suspected recurrence of renal cell carcinoma (RCC) has not been fully evaluated. The purpose of this study was to assess the diagnostic performance of FDG-PET for postoperative assessment in patients with RCC. Methods:We reviewed 28 scans in 23 patients who had undergone FDG-PET scans after surgery for RCC. Diagnostic accuracy of visually interpreted PET was evaluated based on final diagnoses obtained histologically or by clinical follow-up at least 6 months. Also, additional information over CT, influence on treatment decisions, and the accuracy of FDG uptake as a predictor of survival were assessed. Results:Recurrence of renal carcinoma was histologically (n = 15) or clinically (n = 6) confirmed in 21 of 28 cases. Overall, the sensitivity, specificity, and diagnostic accuracy using FDG-PET were 81%, 71%, and 79%, respectively. In papillary RCC, the sensitivity was 100%; however, that was 75% in clear cell RCC in patient-basis. PET correctly detected local recurrence and metastases in all cases in the peritoneum, bone, muscle and adrenal gland. Additional information was obtained from scans in 6 cases (21%), which influenced therapeutic management in 3 cases (11%). Cumulative survival rates over 5 years in the PET-positive vs. the PET-negative group were 46% vs. 83%, respectively (p = 0.17). Conclusions:FDG-PET would be useful for postoperative surveillance in patients with RCC, although its impact on treatment decisions may be limited. Further investigations are necessary to conclude whether PET has a prognostic value. |
著作権等: | © 2009 Elsevier Ireland Ltd. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/143595 |
DOI(出版社版): | 10.1016/j.ejrad.2009.11.019 |
PubMed ID: | 20015602 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。