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|MD5 : f2aa8edbcb8e81432f86da38495ce272|
|Title:||Evolutionary dynamics of spliceosomal intron revealed by in silico analyses of the P-Type ATPase superfamily genes.|
Ohniwa, Ryosuke L
|Author's alias:||小田, 俊之|
|Publisher:||Springer Science+Business Media B.V.|
|Journal title:||Molecular biology reports|
|Abstract:||It has been long debated whether spliceosomal introns originated in the common ancestor of eukaryotes and prokaryotes. In this study, we tested the possibility that extant introns were inherited from the common ancestor of eukaryotes and prokaryotes using in silico simulation. We first identified 21 intron positions that are shared among different families of the P-Type ATPase superfamily, some of which are known to have diverged before the separation of prokaryotes and eukaryotes. Theoretical estimates of the expected number of intron positions shared by different genes suggest that the introns at those 21 positions were inserted independently. There seems to be no intron that arose from before the diversification of the P-Type ATPase superfamily. Namely, the present introns were inserted after the separation of eukaryotes and prokaryotes.|
|Rights:||The final publication is available at www.springerlink.com|
This is not the published version. Please cite only the published version.
|Appears in Collections:||Journal Articles |
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