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Title: Yeast methylotrophy: metabolism, gene regulation and peroxisome homeostasis.
Authors: Yurimoto, Hiroya  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0001-7506-6184 (unconfirmed)
Oku, Masahide  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0001-5991-6281 (unconfirmed)
Sakai, Yasuyoshi  kyouindb  KAKEN_id
Author's alias: 阪井, 康能
Issue Date: 2011
Publisher: Hindawi Publishing Corporation
Journal title: International journal of microbiology
Volume: 2011
Start page: 101298
Abstract: Eukaryotic methylotrophs, which are able to obtain all the carbon and energy needed for growth from methanol, are restricted to a limited number of yeast species. When these yeasts are grown on methanol as the sole carbon and energy source, the enzymes involved in methanol metabolism are strongly induced, and the membrane-bound organelles, peroxisomes, which contain key enzymes of methanol metabolism, proliferate massively. These features have made methylotrophic yeasts attractive hosts for the production of heterologous proteins and useful model organisms for the study of peroxisome biogenesis and degradation. In this paper, we describe recent insights into the molecular basis of yeast methylotrophy.
Rights: © 2011 Hiroya Yurimoto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2433/147268
DOI(Published Version): 10.1155/2011/101298
PubMed ID: 21754936
Appears in Collections:Journal Articles

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