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| File | Description | Size | Format | |
|---|---|---|---|---|
| j.jchromb.2011.04.033.pdf | 828.53 kB | Adobe PDF | View/Open |
| Title: | Identification of novel mammalian phospholipids containing threonine, aspartate, and glutamate as the base moiety. |
| Authors: | Omori, Taketo Honda, Ai Mihara, Hisaaki Kurihara, Tatsuo    https://orcid.org/0000-0002-7777-1378 (unconfirmed)Esaki, Nobuyoshi |
| Author's alias: | 三原, 久明 栗原, 達夫 江崎, 信芳 |
| Keywords: | Aspartate Glutamate Threonine Phospholipids Mammal Carboxylate–phosphate anhydride |
| Issue Date: | 1-Nov-2011 |
| Publisher: | Elsevier B.V. |
| Journal title: | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
| Volume: | 879 |
| Issue: | 29 |
| Start page: | 3296 |
| End page: | 3302 |
| Abstract: | In this study, we showed the occurrence of phosphatidyl-L-threonine (PThr), phosphatidyl-L-aspartate (PAsp), and phosphatidyl-L-glutamate (PGlu) in rat brain. Analyses using an HPLC-ESI-MS and an amino acid analyzer showed the presence of L-threonine, L-aspartate, and L-glutamate in the acid-hydrolysates of phospholipids from porcine cerebrum, rat cerebrum, and rat liver. Results of ESI-MS/MS analyses with neutral loss scanning and product ion scanning suggest the presence of PThr-(18:0, 18:1), PThr-(18:0, 22:6), PAsp-(18:0, 18:1), PAsp-(18:0, 22:6), PGlu-(18:0, 18:1), and PGlu-(18:0, 22:6) in rat brain. This is the first study to identify 2 novel phospholipids, PAsp and PGlu, with a carboxylate-phosphate anhydride bond, in living organisms. |
| Rights: | © 2011 Elsevier B.V. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| URI: | http://hdl.handle.net/2433/151862 |
| DOI(Published Version): | 10.1016/j.jchromb.2011.04.033 |
| PubMed ID: | 21601537 |
| Appears in Collections: | Journal Articles |
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