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Title: Clinical characteristics and risk factors of ocular candidiasis.
Authors: Nagao, Miki  kyouindb  KAKEN_id  orcid (unconfirmed)
Saito, Takashi
Doi, Shoichi
Hotta, Gou
Yamamoto, Masaki  kyouindb  KAKEN_id
Matsumura, Yasufumi  kyouindb  KAKEN_id  orcid (unconfirmed)
Matsushima, Aki  kyouindb  KAKEN_id
Ito, Yutaka
Takakura, Shunji  kyouindb  KAKEN_id
Ichiyama, Satoshi  kyouindb  KAKEN_id
Author's alias: 長尾, 美紀
Keywords: Ocular candidiasis
Risk factors
Fundoscopic investigation
Issue Date: Jun-2012
Publisher: Elsevier Inc.
Journal title: Diagnostic microbiology and infectious disease
Volume: 73
Issue: 2
Start page: 149
End page: 152
Abstract: Ocular candidiasis is a major complication of Candida bloodstream infection (BSI). This study was performed to reveal the clinical characteristics of ocular candidiasis. Of the 220 patients with Candida BSI, 204 cases received ophthalmology consultations between January 2005 and December 2011 at 2 teaching hospitals. Fifty-four (26.5%) cases had findings consistent with the diagnosis of ocular candidiasis. Of these 54 cases, 43 (79.6%) were diagnosed within 7 days after a positive blood culture. Among ocular candidiasis cases, more cases were due to Candida albicans (P =0.034 odds ratio [OR]; 3.68 95% confidence interval [CI] 1.11-12.2) and had higher β-d-glucan values (P = 0.001 OR; 9.99 95% CI 2.60-21.3). We need to consider fundoscopic examination to be performed within the first 7 days of therapy, especially for those patients who have C. albicans BSIs and higher β-d-glucan values. Additionally, follow-up fundoscopic examination should be considered before stopping therapy for high-risk patients.
Rights: © 2012 Elsevier Inc.
This is not the published version. Please cite only the published version.
DOI(Published Version): 10.1016/j.diagmicrobio.2012.03.006
PubMed ID: 22503164
Appears in Collections:Journal Articles

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