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タイトル: 前立腺癌針生検病理組織結果の予測におけるMRIおよび拡散強調像ADC値の有用性
その他のタイトル: Utility of Diffusion-Weighted Magnetic Resonance Imaging and Apparent Diffusion Coefficient in Detection of Prostate Cancer and Prediction of Pathologic Gleason Score
著者: 影林, 頼明  KAKEN_name
中井, 靖  KAKEN_name
松本, 吉弘  KAKEN_name
三馬, 省二  KAKEN_name
宮坂, 俊輝  KAKEN_name
中川, 裕之  KAKEN_name
著者名の別形: Kagebayashi, Yoriaki
Nakai, Yasushi
Matsumoto, Yoshihiro
Samma, Shoji
Miyasaka, Toshiteru
Nakagawa, Hiroyuki
キーワード: Prostate cancer
MRI
Diffusion-weighted imaging
Apparent diffusion coefficient
Gleason score
発行日: Aug-2012
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 58
号: 8
開始ページ: 405
終了ページ: 408
抄録: Thirty patients with histologically proven prostate cancer whose prostate specific antigen values were under 20 ng/ml received magnetic resonance imaging (MRI) at 1.5 T before transrectal ultrasound-guided systematic transrectal 10-core needle biopsy. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) on MRI were retrospectively analyzed by a single radiologist without any information of the results of the biopsy. The locations of cancer, indicated by the results of biopsy, coincided with the findings of MRI in 25 patients (83.3%). The characteristics of DWI and ADC in the lesion with a cancer focus could be analyzed in 21 patients. The mean ADC of cancer lesions was 0.96±0.36×10−3 mm2/sec (±SD). The mean ADC of cancer lesions with a Gleason score of 6 was 1.14±0.40×10−3 mm2/sec, while that of lesions with Gleason scores of 7 and 8 was 0.77±0.20×10−3 mm2/s (p=0.008, unpaired t test). DWI and ADC would be useful parameters in the diagnosis of prostate cancer. ADC of a cancer lesion may indicate the malignant potential of cancer cells represented by the Gleason score.
著作権等: 許諾条件により本文は2013-09-01に公開
URI: http://hdl.handle.net/2433/159772
PubMed ID: 23052263
出現コレクション:Vol.58 No.8

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