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タイトル: | 前立腺癌針生検病理組織結果の予測におけるMRIおよび拡散強調像ADC値の有用性 |
その他のタイトル: | Utility of Diffusion-Weighted Magnetic Resonance Imaging and Apparent Diffusion Coefficient in Detection of Prostate Cancer and Prediction of Pathologic Gleason Score |
著者: | 影林, 頼明 中井, 靖 松本, 吉弘 三馬, 省二 宮坂, 俊輝 中川, 裕之 |
著者名の別形: | Kagebayashi, Yoriaki Nakai, Yasushi Matsumoto, Yoshihiro Samma, Shoji Miyasaka, Toshiteru Nakagawa, Hiroyuki |
キーワード: | Prostate cancer MRI Diffusion-weighted imaging Apparent diffusion coefficient Gleason score |
発行日: | Aug-2012 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 58 |
号: | 8 |
開始ページ: | 405 |
終了ページ: | 408 |
抄録: | Thirty patients with histologically proven prostate cancer whose prostate specific antigen values were under 20 ng/ml received magnetic resonance imaging (MRI) at 1.5 T before transrectal ultrasound-guided systematic transrectal 10-core needle biopsy. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) on MRI were retrospectively analyzed by a single radiologist without any information of the results of the biopsy. The locations of cancer, indicated by the results of biopsy, coincided with the findings of MRI in 25 patients (83.3%). The characteristics of DWI and ADC in the lesion with a cancer focus could be analyzed in 21 patients. The mean ADC of cancer lesions was 0.96±0.36×10−3 mm2/sec (±SD). The mean ADC of cancer lesions with a Gleason score of 6 was 1.14±0.40×10−3 mm2/sec, while that of lesions with Gleason scores of 7 and 8 was 0.77±0.20×10−3 mm2/s (p=0.008, unpaired t test). DWI and ADC would be useful parameters in the diagnosis of prostate cancer. ADC of a cancer lesion may indicate the malignant potential of cancer cells represented by the Gleason score. |
著作権等: | 許諾条件により本文は2013-09-01に公開 |
URI: | http://hdl.handle.net/2433/159772 |
PubMed ID: | 23052263 |
出現コレクション: | Vol.58 No.8 |
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