ダウンロード数: 341
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
RLU.0b013e318238f72b.pdf | 680.54 kB | Adobe PDF | 見る/開く |
タイトル: | Roles and limitations of FDG PET in pediatric non-Hodgkin lymphoma. |
著者: | Nakatani, Koya Nakamoto, Yuji https://orcid.org/0000-0001-5783-8048 (unconfirmed) Watanabe, Kenichiro Saga, Tsuneo https://orcid.org/0000-0001-7801-9316 (unconfirmed) Higashi, Tatsuya Togashi, Kaori |
著者名の別形: | 中谷, 航也 中本, 裕士 |
発行日: | Jul-2012 |
出版者: | Lippincott, Williams & Wilkins |
誌名: | Clinical nuclear medicine |
巻: | 37 |
号: | 7 |
開始ページ: | 656 |
終了ページ: | 662 |
抄録: | [Purpose]: The usefulness of 18F fluorodeoxyglucose (FDG) positron emission tomography (PET) in pediatric Hodgkin lymphoma (p-HL) has been well demonstrated; however, pediatric non-Hodgkin lymphoma (p-NHL) has distinct characteristics from p-HL and adult NHL. We assessed roles of FDG PET in p-NHL. [Materials and Methods]: Nineteen patients with p-NHL underwent 80 scans. Scans for staging (group A, n = 6) and response assessment (group B, n = 42) were compared with conventional imaging modalities (CIMs). Scans within group B for end-chemotherapy assessment (subgroup B+, n = 11) and for post-therapeutic surveillance (group C, n = 32) were analyzed for diagnostic performance. [Results]: In group A, PET and CIM demonstrated comparable results. In group B, PET diagnoses were concordant with CIM in 21 and discordant in 11 studies. Of the discordant cases, PET suggested remnant lesions in 5 cases, whereas CIM suggested lesions in 6 cases. PET modified therapeutic strategy in 4 cases by detecting new extranodal lesions. In subgroup B+, sensitivity, specificity, and accuracy for predicting relapse were 50%, 71%, and 64%, respectively. In group C, sensitivity, specificity, and accuracy were 100%, 87%, and 88%, respectively, but positive predictive value was 33%. [Conclusions]: The role of FDG PET in p-NHL may be limited, unlike with p-HL or adult NHL. Nevertheless, FDG PET may serve complementarily in detecting unexpected lesions that can emerge in p-NHL. |
著作権等: | © 2012 Lippincott Williams & Wilkins. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/177069 |
DOI(出版社版): | 10.1097/RLU.0b013e318238f72b |
PubMed ID: | 22691506 |
関連リンク: | http://hdl.handle.net/2433/157424 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。