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ファイル | 記述 | サイズ | フォーマット | |
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j.mehy.2013.10.017.pdf | 277.64 kB | Adobe PDF | 見る/開く |
タイトル: | Reconsideration of animal models of schizophrenia and other psychiatric disorders with evolutionary perspective. |
著者: | Lee, Young-A Goto, Yukiori |
著者名の別形: | 後藤, 幸織 |
発行日: | Dec-2013 |
出版者: | Elsevier Ltd. |
誌名: | Medical hypotheses |
巻: | 81 |
号: | 6 |
開始ページ: | 1120 |
終了ページ: | 1126 |
抄録: | Studies utilizing animal models for understanding biological mechanisms of such psychiatric disorders as schizophrenia have been now flourishing. Animal models are a essential part of translational research, and without them, it is not possible to develop therapeutic strategies to treat psychiatric disorders. Accordingly, importance of animal models has been increasingly emphasized. However, on the other side, limitations of such an animal model approach have been growingly deceptive. The aim of this review article is to discuss limitations of translational research utilizing animal models, and propose a new direction of research with evolutionary perspective to understand psychiatric disorders. |
著作権等: | © 2013 Elsevier Ltd. この論文は著者最終稿です。内容が印刷版と異なることがありますので、引用の際には出版社版をご確認ご利用ください。This is the Accepted Author Manuscript. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/179780 |
DOI(出版社版): | 10.1016/j.mehy.2013.10.017 |
PubMed ID: | 24199948 |
出現コレクション: | 学術雑誌掲載論文等 |
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