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タイトル: | 2009年版TNM分類によるpT3aN0M0腎細胞癌の再発危険因子の検討 |
その他のタイトル: | Risk Factors for Recurrence in pT3aN0M0 Renal cell Carcinoma According to 2009 TNM Classification |
著者: | 宇都宮, 紀明 河野, 有香 松本, 敬優 住吉, 崇幸 増田, 憲彦 白石, 裕介 根来, 宏光 常森, 寛行 杉野, 善雄 大久保, 和俊 岡田, 卓也 清川, 岳彦 六車, 光英 川喜田, 睦司 |
著者名の別形: | Utsunomiya, Noriaki Kono, Yuka Matsumoto, Keiyu Sumiyoshi, Takayuki Masuda, Norihiko Shiraishi, Yusuke Negoro, Hiromitsu Tsunemori, Hiroyuki Sugino, Yoshio Okubo, Kazutoshi Okada, Takuya Segawa, Takehiko Muguruma, Koei Kawakita, Mutsushi |
キーワード: | RCC pT3aN0M0 2009 TNM |
発行日: | Jan-2014 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 60 |
号: | 1 |
開始ページ: | 1 |
終了ページ: | 5 |
抄録: | The TNM classification of renal cell carcinoma was updated in 2009. In this new classification system, T3a consists of tumors with renal vein involvement and tumors with fat invasion. To assess risk factors for recurrence, we retrospectively reviewed 89 patients with pT3aN0M0 renal cell carcinoma who underwent radical or partial nephrectomy between 1992 and 2011. Analyzed risk factors for recurrence were age, gender, tumor size, grade, v factor, infiltrative growth (INF), adjuvant interferon, surgical technic (radical or partial), clinical T classification, renal vein thrombus, and pathological fat invasion. The median follow-up was 52.2 months. Five-year recurrence-free survival rate was 69.0%. Within the pT3a subcategory, the five-year recurrence-free survival was 76.7% in patients with fat invasion only, 42.9% in patients with renal vein thrombus only, and 28.6% in patients with the two concomitant features. On univariate analysis, tumor size, grade, INF, clinical T classification, and renal vein thrombus were significantly associated with recurrence. On multivariate analysis, INF (p=0. 023, HR 3. 927) was an independent risk factor for recurrence. In pT3aN0M0 renal cell carcinoma, INF significantly affects recurrence, and patients with both fat invasion and renal vein thrombus have worst prognosis. |
著作権等: | 許諾条件により本文は2015-02-01に公開 |
URI: | http://hdl.handle.net/2433/182920 |
PubMed ID: | 24594765 |
出現コレクション: | Vol. 60 No. 1 |
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