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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 10641955.2013.784780.pdf | 349.76 kB | Adobe PDF | 見る/開く |
| タイトル: | Endothelial function progressively deteriorates during normal pregnancy. |
| 著者: | Fujita, Kohei Tatsumi, Keiji Kondoh, Eiji   https://orcid.org/0000-0002-8379-3143 (unconfirmed)Chigusa, Yoshitsugu  https://orcid.org/0000-0001-9629-5912 (unconfirmed)Mogami, Haruta https://orcid.org/0000-0002-9481-6320 (unconfirmed)Fujita, Masatoshi Konishi, Ikuo |
| 著者名の別形: | 藤田, 浩平 |
| キーワード: | Endothelial function peripheral arterial tonometry pregnancy sFlt-1 preeclampsia |
| 発行日: | May-2013 |
| 出版者: | Informa Healthcare |
| 誌名: | Hypertension in pregnancy |
| 巻: | 32 |
| 号: | 2 |
| 開始ページ: | 129 |
| 終了ページ: | 138 |
| 抄録: | Objective: To elucidate changes in endothelial function throughout the gestational period in normal pregnancy and its relationship with plasma soluble fms-like tyrosine kinase-1 (sFlt-1) levels. Methods: Endothelial function was evaluated by reactive hyperemia index (RHI) using Endo-PAT2000 and plasma sFlt-1 levels were measured simultaneously by ELISA. Results: RHI gradually deteriorated with increasing gestational age. Plasma sFlt-1 levels exhibited a gradual increase at late pregnancy and were inversely correlated with RHI. Conclusion: Maternal endothelial function gradually deteriorates with increasing gestational age and there is an inverse correlation between endothelial function and plasma sFlt-1 levels in normal pregnancy. |
| 著作権等: | © 2013 Informa Healthcare. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
| URI: | http://hdl.handle.net/2433/189762 |
| DOI(出版社版): | 10.3109/10641955.2013.784780 |
| PubMed ID: | 23725078 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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