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ファイル | 記述 | サイズ | フォーマット | |
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02648725.2013.801236.pdf | 192.81 kB | Adobe PDF | 見る/開く |
タイトル: | Post-transcriptional regulation of cytokine mRNA controls the initiation and resolution of inflammation. |
著者: | Mino, Takashi https://orcid.org/0000-0002-9562-008X (unconfirmed) Takeuchi, Osamu https://orcid.org/0000-0002-1260-6232 (unconfirmed) |
著者名の別形: | 三野, 享史 竹内, 理 |
キーワード: | post-transcriptional regulation inflammation cytokine mRNA stability regnase-1 (Zc3h12a, Mcpip1) |
発行日: | 24-Jul-2013 |
出版者: | Taylor & Francis |
誌名: | Biotechnology & genetic engineering reviews |
巻: | 29 |
開始ページ: | 49 |
終了ページ: | 60 |
抄録: | Cytokines are critical mediators of inflammation and host defense. Cytokine production is regulated during transcription and post-transcription. Post-transcriptional regulation modifies mRNA stability and translation, allowing for the rapid and flexible control of gene expression, which is important for coordinating the initiation and resolution of inflammation. We review here a variety of post-transcriptional control mechanisms that regulate inflammation and discuss how these mechanisms are integrated to coordinate this essential process. |
著作権等: | This is an Accepted Manuscript of an article published in "Biotechnology and Genetic Engineering Reviews" on 07/24/2013, available online: http://www.tandfonline.com/10.1080/02648725.2013.801236 This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/189774 |
DOI(出版社版): | 10.1080/02648725.2013.801236 |
PubMed ID: | 24568252 |
出現コレクション: | 学術雑誌掲載論文等 |
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