ダウンロード数: 303
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
s00417-012-2137-y.pdf | 355.69 kB | Adobe PDF | 見る/開く |
タイトル: | Two-year outcome of photodynamic therapy combined with intravitreal injection of bevacizumab and triamcinolone acetonide for polypoidal choroidal vasculopathy. |
著者: | Nakata, Isao Tsujikawa, Akitaka Yamashiro, Kenji Otani, Atsushi Ooto, Sotaro Akagi-Kurashige, Yumiko Ueda-Arakawa, Naoko Iwama, Daisuke Yoshimura, Nagahisa |
著者名の別形: | 辻川, 明孝 |
キーワード: | Age-related macular degeneration Bevacizumab Photodynamic therapy Polypoidal choroidal vasculopathy Triamcinolone acetonide |
発行日: | Apr-2013 |
出版者: | Springer-Verlag |
誌名: | Graefe's archive for clinical and experimental ophthalmology |
巻: | 251 |
号: | 4 |
開始ページ: | 1073 |
終了ページ: | 1080 |
抄録: | [Purpose]To compare the 2-year results after photodynamic therapy (PDT) alone and PDT combined with intravitreal injections of bevacizumab and triamcinolone acetonide (triple therapy) for polypoidal choroidal vasculopathy (PCV). [Methods]We retrospectively reviewed the medical records of 40 consecutive patients (40 eyes) with subfoveal PCV. Of these 40 eyes, 16 were treated with PDT alone and 24 were treated with triple therapy. [Results]The change in visual acuity in the triple therapy group was significantly better than that in the PDT group (P < 0.001). At 24 months, improvement in visual acuity was seen in only two eyes (12.5 %) of the PDT group, while it was seen in ten eyes (41.7 %) of the triple therapy group. Retreatment was given to 12 eyes (75.0 %) in the PDT group and to nine eyes (37.5 %) in the triple therapy group, although the retreatment-free period was significantly longer in the triple therapy group than in the PDT group (P < 0.001). Post-treatment vitreous hemorrhage was seen in only two eyes (12.5 %), all of which were in the PDT group. [Conclusion]Compared with PDT alone, triple therapy appears to reduce the postoperative hemorrhagic complications and recurrences of PCV and to improve the 2-year visual outcomes of PCV. |
著作権等: | The final publication is available at Springer via http://dx.doi.org/10.1007/s00417-012-2137-y This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/189826 |
DOI(出版社版): | 10.1007/s00417-012-2137-y |
PubMed ID: | 22923282 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。