ダウンロード数: 1050
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
PAF.0b013e31828879cd.pdf | 1.02 MB | Adobe PDF | 見る/開く |
タイトル: | The effectiveness and limitations of triphenyltetrazolium chloride to detect acute myocardial infarction at forensic autopsy. |
著者: | Kakimoto, Yu Tsuruyama, Tatsuaki Miyao, Masashi Abiru, Hitoshi Sumiyoshi, Shinji Kotani, Hirokazu Haga, Hironori Tamaki, Keiji |
著者名の別形: | 垣本, 由布 玉木, 敬二 |
キーワード: | TTC myocardial infarction sudden death postmortem interval postmortem diagnosis |
発行日: | Sep-2013 |
出版者: | Lippincott Williams & Wilkins |
誌名: | The American journal of forensic medicine and pathology |
巻: | 34 |
号: | 3 |
開始ページ: | 242 |
終了ページ: | 247 |
抄録: | Triphenyltetrazolium chloride (TTC) is one of the most conventional stains to detect infarcted area of the heart in animal experiments. However, its availability and limitations have not been thoroughly discussed in the forensic field. Here, authors stained human hearts with TTC soon after the harvest. Photographs of the samples were analyzed using image analysis software, which evaluated the occupying ratio of the stained area on the surface of each slice. The results showed that the stainability of TTC declines with the length of the postmortem interval (PMI). Specimens reacted well to TTC within 1.5 days after death and then decreased the stainability logarithmically with PMI (y = - 0.294 In (x) + 1.0441; x = PMI, y = TTC-stained area total myocardial area, R = 0.5673). Samples with old myocardial infarction produced clear TTC contrast; normal tissue is vivid red, and fibrotic myocardium is white discoloration. In acute myocardial infarction cases where death occurred within 9 hours after the attack, however, the detection of infarcted area was very difficult even when PMI was less than 1.5 days. In summary, the TTC method may be useful within 1.5 days after death, but short suffering period before death disturbs its staining efficiency. |
著作権等: | © 2013 by Lippincott Williams & Wilkins. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/189846 |
DOI(出版社版): | 10.1097/PAF.0b013e31828879cd |
PubMed ID: | 23949140 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。