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| File | Description | Size | Format | |
|---|---|---|---|---|
| c3ob41823e.pdf | 641.38 kB | Adobe PDF | View/Open |
| Title: | CGmCGCG is a versatile substrate with which to evaluate Tet protein activity. |
| Authors: | Kizaki, Seiichiro Sugiyama, Hiroshi    https://orcid.org/0000-0001-8923-5946 (unconfirmed) |
| Author's alias: | 木崎, 誠一朗 杉山, 弘 |
| Issue Date: | 7-Jan-2014 |
| Publisher: | Royal Society of Chemistry (RSC) |
| Journal title: | Organic & Biomolecular Chemistry |
| Volume: | 12 |
| Issue: | 1 |
| Start page: | 104 |
| End page: | 107 |
| Abstract: | Tet family proteins have the ability to convert 5-methylcytosine (mC) to 5-hydroxymethylcytosine, and further to 5-formylcytosine and 5-carboxycytosine. We found that CGmCGCG can be the substrate of Tet protein, and observed iterative oxidation of mC by HPLC analysis. We also demonstrated that Tet protein favours single-stranded DNA over double-stranded DNA. |
| Rights: | ©The Royal Society of Chemistry 2014 This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| URI: | http://hdl.handle.net/2433/193040 |
| DOI(Published Version): | 10.1039/c3ob41823e |
| PubMed ID: | 24162071 |
| Appears in Collections: | Journal Articles |
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