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Title: Decrease of muscle volume in chronic kidney disease: the role of mitochondria in skeletal muscle.
Authors: Yokoi, Hideki  kyouindb  KAKEN_id
Yanagita, Motoko  kyouindb  KAKEN_id
Author's alias: 横井, 秀基
柳田, 素子
Issue Date: Jun-2014
Publisher: Nature Publishing Group
Journal title: Kidney international
Volume: 85
Issue: 6
Start page: 1258
End page: 1260
Abstract: Reduced muscle volume and impaired exercise endurance are well-documented phenomena in chronic kidney disease, and the relevant molecular mechanisms have been gradually unveiled. Tamaki et al. demonstrate a reduction of mitochondria content in skeletal muscles as a novel mechanism of reduced exercise endurance in renal insufficiency. In addition, they show that a high-protein diet reduces exercise endurance through an inhibition of muscle pyruvate dehydrogenase.
Rights: © 2014 International Society of Nephrology
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。This is not the published version. Please cite only the published version.
DOI(Published Version): 10.1038/ki.2013.539
PubMed ID: 24875545
Appears in Collections:Journal Articles

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