ダウンロード数: 256
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
jlcr.3232.pdf | 591.95 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | Kimura, Hiroyuki | en |
dc.contributor.author | Yagi, Yusuke | en |
dc.contributor.author | Ohneda, Noriyuki | en |
dc.contributor.author | Odajima, Hiro | en |
dc.contributor.author | Ono, Masahiro | en |
dc.contributor.author | Saji, Hideo | en |
dc.contributor.alternative | 木村, 寛之 | ja |
dc.contributor.alternative | 佐治, 英郎 | ja |
dc.date.accessioned | 2015-07-02T04:35:27Z | - |
dc.date.available | 2015-07-02T04:35:27Z | - |
dc.date.issued | 2014-08-08 | - |
dc.identifier.issn | 0362-4803 | - |
dc.identifier.uri | http://hdl.handle.net/2433/198616 | - |
dc.description.abstract | Microwave technology has been successfully applied to enhance the effectiveness of radiolabeling reactions. The use of a microwave as a source of heat energy can allow chemical reactions to proceed over much shorter reaction times and in higher yields than they would do under conventional thermal conditions. A microwave reactor developed by Resonance Instrument Inc. (Model 520/521) and CEM (PETWave) has been used exclusively for the synthesis of radiolabeled agents for positron emission tomography by numerous groups throughout the world. In this study, we have developed a novel resonant-type microwave reactor powered by a solid-state device and confirmed that this system can focus microwave power on a small amount of reaction solution. Furthermore, we have demonstrated the rapid and facile radiosynthesis of 16α-[(18)F]fluoroestradiol, 4-[(18)F]fluoro-N-[2-(1-methoxyphenyl)-1-piperazinyl]ethyl-N-2-pyridinylbenzamide, and N-succinimidyl 4-[(18)F]fluorobenzoate using our newly developed microwave reactor. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley | en |
dc.rights | This is the peer reviewed version of the following article: Kimura H., Yagi Y., Ohneda N., Odajima H., Ono M., and Saji H. (2014), Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals, J. Label Compd. Radiopharm, 57, pages 680–686, which has been published in final form at http://dx.doi.org/10.1002/jlcr.3232. | en |
dc.rights | 許諾条件により本文ファイルは2015-08-08に公開. | ja |
dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
dc.rights | This is not the published version. Please cite only the published version. | en |
dc.subject | resonant-type microwave reactor | en |
dc.subject | positron emission tomography radiochemistry | en |
dc.subject | [18F]-fluorination | en |
dc.subject | [18F]FES | en |
dc.subject | [18F]MPPF | en |
dc.subject | [18F]SFB | en |
dc.title | Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals. | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.ncid | AA00701124 | - |
dc.identifier.jtitle | Journal of labelled compounds & radiopharmaceuticals | en |
dc.identifier.volume | 57 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 680 | - |
dc.identifier.epage | 686 | - |
dc.relation.doi | 10.1002/jlcr.3232 | - |
dc.textversion | author | - |
dc.startdate.bitstreamsavailable | 2015-08-08 | - |
dc.identifier.pmid | 25294422 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0362-4803 | - |
dc.identifier.eissn | 1099-1344 | - |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。