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タイトル: Itraconazole prophylaxis for invasive Aspergillus infection in lung transplantation.
著者: Kato, K  kyouindb  KAKEN_id
Nagao, M  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-8886-6145 (unconfirmed)
Nakano, S  KAKEN_id
Yunoki, T
Hotta, G
Yamamoto, M  kyouindb  KAKEN_id
Matsumura, Y  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0001-8595-8944 (unconfirmed)
Ito, Y
Takakura, S
Chen, F
Bando, T
Matsuda, Y
Matsubara, K  KAKEN_id
Date, H  kyouindb  KAKEN_id
Ichiyama, S  KAKEN_id
著者名の別形: 長尾, 美紀
キーワード: lung transplantation
itraconazole
invasive Aspergillus infection
therapeutic drug monitoring
prophylaxis duration
発行日: Apr-2014
出版者: wiley
誌名: Transplant infectious disease
巻: 16
号: 2
開始ページ: 340
終了ページ: 343
抄録: Invasive Aspergillus infection (IA) is a significant cause of morbidity in lung transplantation (LT). However, its optimal prophylaxis is unclear. We routinely administer itraconazole (ITCZ) prophylaxis to all patients undergoing LT. In this study, we retrospectively evaluated the duration of prophylaxis and risk factors of IA. Among 30 adult patients who underwent LT, 5 patients developed IA. All patients with IA stopped ITCZ treatment within 1 year. At least 1 year of ITCZ prophylaxis is essential for the prevention of IA. Cytomegalovirus infection, renal replacement therapy, and tracheotomy were risk factors for IA.
著作権等: This is the peer reviewed version of the following article: K. Kato, M. Nagao, S. Nakano, T. Yunoki, G. Hotta, M. Yamamoto, Y. Matsumura, Y. Ito, S. Takakura, F. Chen, T. Bando, Y. Matsuda, K. Matsubara, H. Date, S. Ichiyama. Itraconazole prophylaxis for invasive Aspergillus infection in lung transplantation. Transpl Infect Dis 2014: 16: 340–343, which has been published in final form at http://dx.doi.org/10.1111/tid.12187. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
This is not the published version. Please cite only the published version.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/199863
DOI(出版社版): 10.1111/tid.12187
PubMed ID: 24593162
出現コレクション:学術雑誌掲載論文等

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