|Title:||Boosting of activity enhancement of K(+)-responsive quadruplex hammerhead ribozyme.|
|Authors:||Yamaoki, Yudai https://orcid.org/0000-0002-8927-4985 (unconfirmed)|
Nagata, Takashi https://orcid.org/0000-0002-3733-2709 (unconfirmed)
Katahira, Masato https://orcid.org/0000-0003-0336-7660 (unconfirmed)
|Author's alias:||片平, 正人|
|Publisher:||Royal Society of Chemistry|
|Journal title:||Chemical communications|
|Abstract:||Two second-generation quadruplex hammerhead ribozymes, whose activity enhances in response to K(+)via quadruplex formation of embedded r(GGA)3GG, were developed. Different strategies were applied to suppress basal activity when K(+) is absent. As a result, the activity enhancement upon the addition of K(+) has reached as high as 21-fold.|
|Description:||Accepted 13 Feb 2015.|
|Rights:||This journal is © The Royal Society of Chemistry 2015.|
The full-text file will be made open to the public on 13 Feb 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
This is not the published version. Please cite only the published version.
|Appears in Collections:||Journal Articles|
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