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Title: Boosting of activity enhancement of K(+)-responsive quadruplex hammerhead ribozyme.
Authors: Yamaoki, Yudai  kyouindb  KAKEN_id  orcid (unconfirmed)
Mashima, Tsukasa  kyouindb  KAKEN_id
Nagata, Takashi  kyouindb  KAKEN_id  orcid (unconfirmed)
Katahira, Masato  kyouindb  KAKEN_id  orcid (unconfirmed)
Author's alias: 片平, 正人
Issue Date: 2-Mar-2015
Publisher: Royal Society of Chemistry
Journal title: Chemical communications
Volume: 51
Issue: 27
Start page: 5898
End page: 5901
Abstract: Two second-generation quadruplex hammerhead ribozymes, whose activity enhances in response to K(+)via quadruplex formation of embedded r(GGA)3GG, were developed. Different strategies were applied to suppress basal activity when K(+) is absent. As a result, the activity enhancement upon the addition of K(+) has reached as high as 21-fold.
Description: Accepted 13 Feb 2015.
Rights: This journal is © The Royal Society of Chemistry 2015.
The full-text file will be made open to the public on 13 Feb 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
This is not the published version. Please cite only the published version.
DOI(Published Version): 10.1039/c5cc00961h
PubMed ID: 25727931
Appears in Collections:Journal Articles

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