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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| cbic.201500140.pdf | 1.57 MB | Adobe PDF | 見る/開く |
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| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Syed, Junetha | en |
| dc.contributor.author | Chandran, Anandhakumar | en |
| dc.contributor.author | Pandian, Ganesh N | en |
| dc.contributor.author | Taniguchi, Junichi | en |
| dc.contributor.author | Sato, Shinsuke | en |
| dc.contributor.author | Hashiya, Kaori | en |
| dc.contributor.author | Kashiwazaki, Gengo | en |
| dc.contributor.author | Bando, Toshikazu | en |
| dc.contributor.author | Sugiyama, Hiroshi | en |
| dc.contributor.alternative | 杉山, 弘 | ja |
| dc.date.accessioned | 2015-11-17T00:35:32Z | - |
| dc.date.available | 2015-11-17T00:35:32Z | - |
| dc.date.issued | 2015-05-28 | - |
| dc.identifier.issn | 1439-7633 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/201619 | - |
| dc.description.abstract | Small molecules capable of modulating epigenetic signatures can activate the transcription of tissue-restricted genes in a totally unrelated cell type and have potential use in epigenetic therapy. To provide an example for an initial approach, we report here on one synthetic small-molecule compound-termed "SAHA-PIP X"-from our library of conjugates. This compound triggered histone acetylation accompanied by the transcription of retinal-tissue-related genes in human dermal fibroblasts (HDFs). | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | wiley | en |
| dc.rights | This is the peer reviewed version of the following article: Syed, J., Chandran, A., Pandian, G. N., Taniguchi, J., Sato, S., Hashiya, K., Kashiwazaki, G., Bando, T. and Sugiyama, H. (2015), A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. ChemBioChem, 16: 1497–1501, which has been published in final form at http://dx.doi.org/10.1002/cbic.201500140. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. | en |
| dc.rights | The full-text file will be made open to the public on 28 May 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. | en |
| dc.rights | This is not the published version. Please cite only the published version. | en |
| dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
| dc.subject | artificial transcription activators | en |
| dc.subject | DNA recognition | en |
| dc.subject | gene expression | en |
| dc.subject | histone acetylation | en |
| dc.subject | transcription profiling | en |
| dc.title | A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.ncid | AA11497584 | - |
| dc.identifier.jtitle | Chembiochem | en |
| dc.identifier.volume | 16 | - |
| dc.identifier.issue | 10 | - |
| dc.identifier.spage | 1497 | - |
| dc.identifier.epage | 1501 | - |
| dc.relation.doi | 10.1002/cbic.201500140 | - |
| dc.textversion | author | - |
| dc.startdate.bitstreamsavailable | 2016-05-28 | - |
| dc.identifier.pmid | 25900774 | - |
| dcterms.accessRights | open access | - |
| 出現コレクション: | 学術雑誌掲載論文等 | |
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