Downloads: 157

Files in This Item:
File Description SizeFormat 
s40064-015-1339-2.pdf933.03 kBAdobe PDFView/Open
Title: Increased bone marrow uptake of 18F-FDG in leukemia patients: preliminary findings.
Authors: Arimoto, Maya Kato
Nakamoto, Yuji  kyouindb  KAKEN_id  orcid (unconfirmed)
Nakatani, Koya
Ishimori, Takayoshi  kyouindb  KAKEN_id
Yamashita, Kouhei
Takaori-Kondo, Akifumi
Togashi, Kaori
Author's alias: 中本, 裕士
Keywords: Leukemia
Bone marrow
Issue Date: 17-Sep-2015
Publisher: SpringerOpen
Journal title: SpringerPlus
Volume: 4
Thesis number: 521
Abstract: The aim of this retrospective study was to evaluate the characteristics of increased bone marrow uptake of 18F-FDG in patients with leukemia who underwent whole-body 18F-FDG PET/CT. The 18F-FDG PET/CT images of 9 patients with histologically proven leukemia were reviewed. The accumulation of 18F-FDG in the bone marrow was evaluated, and was compared with histological subtype, clinical course, and hematological findings. Nine patients (4 males, 5 females; age range, 5-58 years) had increased bone marrow uptake of 18F-FDG, including 6 patients with acute lymphoblastic leukemia, 1 with acute myeloid leukemia, 1 with chronic myeloid leukemia, and 1 with mature B cell neoplasm. Bone marrow uptake was generally diffuse but focal or inhomogeneous uptake was common, especially in the upper and lower extremities. Patients with increased bone marrow uptake of 18F-FDG commonly complained of fever and bone pain. No correlations between 18F-FDG uptake and peripheral blood findings were observed. Patients with leukemia may have increased bone marrow uptake of 18F-FDG on PET/CT, possibly reflecting leukemic cell activity. Leukemia can be included in the differential diagnosis when increased bone marrow uptake of 18F-FDG is observed.
Rights: © 2015 Arimoto et al.
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
DOI(Published Version): 10.1186/s40064-015-1339-2
PubMed ID: 26405641
Appears in Collections:Journal Articles

Show full item record

Export to RefWorks

Export Format: 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.